Rays vs. Yankees Prediction & Picks: MLB Odds & Best Bets for Wednesday, Sept. 23

My Rays vs. Yankees prediction breaks down the best bets, player props, and home run pick Iโ€™m betting today.
Yankees first baseman Paul Goldschmidt (48) walks to first base as we break down our Rays vs. Yankees prediction.
Pictured: Yankees first baseman Paul Goldschmidt (48) walks to first base as we break down our Rays vs. Yankees prediction. Photo by David Frerker / Imagn Images.
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The Rays won the AL East last night, but my Rays vs. Yankees prediction expects New York to bounce back today at home.

My MLB picks back the Yankees as a -136 betting favorite, with Gerrit Cole and Ian Seymour squaring off. First pitch from Yankee Stadium in the Bronx, N.Y., is set for 7:05 p.m. ET (Prime Video, MLB.TV).


โšพ Rays vs. Yankees picks & odds today

See all of our expertsโ€™ MLB picks based on the latest MLB odds.

Pick Best Odds Bet size
Yankees ML -136 via DraftKings 2.04 units to win 1.5 units
Paul Goldschmidt Over 1.5 hits+runs+RBIs +115 via BetMGM 1.3 units to win 1.5 units
Ben Rice Over 0.5 home runs +470 via FanDuel 0.43 units to win 2 units

Total wagered: 3.77 units | Max profit: +5 units

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๐Ÿ’ฐ Rays vs. Yankees prediction & best bet

Yankees ML (-136 via DraftKings)

While today's game has no playoff implications, one team will be playing for pride after watching its division rival clinch the AL East at Yankee Stadium.

Morale can't be high in the Yankees' clubhouse with Aaron Judge injured and the Rays winning the AL East. However, that's the kind of motivation we want to target in a game with no playoff implications. The Rays will likely be fat and happy after securing a first-round bye, while the Yankees will be looking for revenge with a former Cy Young winner on the mound.

Yankees ML (-136) is the best line available among the top MLB betting sites.

Score prediction: Yankees 4, Rays 3  

📡 SBR Edge: Cole World

Current Rays hitters are slashing just .242/.294/.336 against Cole across 149 career at-bats.


๐Ÿ”ฅ Best Rays vs. Yankees player prop bet

Paul Goldschmidt Over 1.5 hits+runs+RBIs (+115 via BetMGM)

Not only has Goldschmidt gone over this line in three of his last five home games, but he also has a favorable pitching matchup today with Seymour starting for the Rays. Goldschmidt is slashing .307/.402/.588 against left-handed pitching, much better than his slash line against righties (.207/.234/.342).

This line is -102 at DraftKings, so grab the value at BetMGM before the market fully accounts for Goldschmidt's splits against lefties. Goldschmidt Over 1.5 hits+runs+RBIs (+115) is the best line available among the top sports betting sites.

💵 More MLB props today

Looking for more? Dive into Mike Spector's best NRFI bets today.


๐Ÿ’ฃ Rays vs. Yankees home run prediction

Ben Rice Over 0.5 home runs (+470 via FanDuel)

Rice owns Seymour. The Yankees designated hitter is 3-for-6 against Seymour in his career, with two home runs.

Not only that, but he's also homered in four of his last 16 games, so it's not like he's been struggling to hit for power lately. With weather likely to have a minimal impact tonight in the Bronx, there's no reason Rice can't hit his third home run against Seymour.

Rice Over 0.5 home runs (+470) is the best line available among the top sports betting apps.


๐Ÿ“Š Live Rays vs. Yankees odds


๐Ÿš‘ Rays vs. Yankees injuries


๐Ÿ“บ How to watch Rays vs. Yankees

  • Date: Wednesday, Sept. 23
  • First pitch: 7:05 p.m. ET
  • Ballpark: Yankee Stadium (Bronx, N.Y.)
  • TV: Prime Video, MLB.TV
  • Rays starter: Ian Seymour (9-7, 4.38 ERA)
  • Yankees starter: Gerrit Cole (9-9, 3.63 ERA)