Giants vs. Dodgers Prediction & Picks: MLB Odds for Tonight, Sept. 18
Last Updated: September 18, 2026 5:38 AM EDT β’ 3 minute read X Social Google News Link
The Dodgers have officially wrapped up the NL West and will now look to earn the No. 1 seed, as their starter Tyler Glasnow takes on the Giants' starter, Cesar Perdomo. The Dodgers are -313 favorites.
My best Giants vs. Dodgers prediction anticipates a lot of runs, as Perdomo faces the Dodgers offense for the first time and Glasnow struggles to regain his early-season form. My MLB picks for tonight's 10:10 p.m. ET game at Dodger Stadium also include a player prop and home run bet. This contest will air locally and stream on Apple TV.
βΎ Giants vs. Dodgers picks & odds today
See all of our expertsβ MLB picks based on the latest MLB odds.
| Pick | Best Odds | Units |
|---|---|---|
| Over 8 | -105 via Caesars | 2 units to win 1.91 units |
| Cesar Perdomo Under 2.5 strikeouts | +130 via FanDuel | 1.5 units to win 1.95 units |
| Freddie Freeman to hit a home run | +560 via FanDuel | 0.25 units to win 1.4 units |
Total wagered: 3.75 units | Max profit: 5.26 units
📃 Affiliate disclosure
Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
π Who will win Giants vs. Dodgers?
I'm taking the Dodgers to win this one 7-5. Perdomo finally showed some issues in his last start, and I expect his struggles to continue against the league's fourth-highest-scoring offense.
Score prediction: Dodgers 7 Giants 5
π° Giants vs. Dodgers prediction & best bet
Over 8 (-105)
After his first 10 innings in the MLB, Perdomo had allowed only six hits and one earned run. That all changed on Saturday, when the Padres, who rank in the bottom 10 in runs scored, lit him up for 10 hits and five runs.
But I also expect Glasnow to struggle. In April, he pitched 8 innings against the Giants and allowed just one hit. However, he hasn't been the same since returning from the IL in late August. He's allowed 12 earned runs in his last four starts, as his ERA has drifted from 2.72 to 3.50.
📡 SBR Edge: Giants' offense has been solid of late
The Giants rank 23rd in runs scored, but they enter this game having scored at least five runs in five of their last seven contests.
π₯ Best Giants vs. Dodgers player prop bet
Cesar Perdomo Under 2.5 strikeouts (+130)
Perdomo has struck out at least three batters in each of his three starts, but that's where the good news ends. He's averaging just 0.75 strikeouts per inning, and he's failed to reach 5.0 innings in two of his appearances.
Perhaps more importantly, the Dodgers are the fifth-least strikeout-prone team in the league. Meanwhile, the two teams Perdomo struck out four times have the fourth-most and 14th-most strikeouts this season. The price of -166 implies a 62.41% chance Perdomo hits this Over. With a ceiling of four strikeouts, the Under has too much value to pass up.
π£ Giants vs. Dodgers home run prediction
Freddie Freeman to hit a home run (+560)
Freeman has only hit one home run since July 5, but he's still my favorite pick for this game. Though his barrel rate has dropped to just 7.9%, that's still better than Mookie Betts and Kyle Tucker, two batters with less favorable prices tonight.
Perdomo has allowed two home runs in his three starts, and he has a hard-hit percentage of 47.8%. That's 10.7% above the league average.
π Live Giants vs. Dodgers odds
π Giants vs. Dodgers betting trends
| Giants | Statistic | Dodgers |
|---|---|---|
| 64-89 | W-L record | 93-60 |
| 80-73 | Run line record | 63-90 |
| 74-67-12 | O/U record | 70-79-4 |
| 5-5 | Last 10 games | 7-3 |
| 4.34 | Team ERA | 3.65 |
| .248 | Team batting avg. | .255 |
| .717 | OPS | .759 |
π Giants vs. Dodgers injuries
πΊ How to watch Giants vs. Dodgers
- Date: Friday, Sept. 18
- First pitch: 10:10 p.m. ET
- Ballpark: Dodger Stadium (Los Angeles)
- TV: Local
- Streaming: Apple TV
- Giants starter: Cesar Perdomo (0-1, 3.68 ERA)
- Dodgers starter: Tyler Glasnow (4-1, 3.50 ERA)
Philip Wood X social