Lions vs. Bills Same-Game Parlay: Week 2 SGP Picks & Odds
My Lions vs. Bills same-game parlay anticipates a high-scoring game tonight on Thursday Night Football.
The Bills are a 5.5-point betting favorite, with kickoff from the new Highmark Stadium in Orchard Park, N.Y., set for 8:15 p.m. ET (Prime Video).
🏈 Lions vs. Bills same-game parlay: Week 2
See the latest NFL odds and our experts' NFL picks for every game this season.
| Parlay leg | Odds |
|---|---|
| Josh Allen Over 253.5 passing yards | -111 via FanDuel |
| DJ Moore 70+ receiving yards | +120 via DraftKings |
| Jared Goff Over 268.5 passing yards | -113 via FanDuel |
Best SGP odds: +440 via DraftKings | Bet size: 1 unit
🚀 Lions vs. Bills parlay picks
Josh Allen Over 253.5 passing yards (-111 via DraftKings)
Josh Allen has a dream matchup Thursday against a Lions defense that permitted Tyler Shough to rack up an almost incomprehensible 410 passing yards in Week 1.
Detroit’s secondary had sporadic struggles a season ago, ranking 19th in passing defense on a per game basis, but it seems to be even more ripe for the picking in 2026 as their tendency as a pass funnel defense continues.
DJ Moore 70+ receiving yards (+120 via DraftKings)
In line with the expectation for Allen to sail beyond his passing yardage line, I like DJ Moore to contribute another big game after going for five receptions and 100 receiving yards in his Buffalo debut.
While Dalton Kincaid saw even more robust receiving production in Week 1, racking up 130 yards, I like Moore as the primary beneficiary this week facing a Detroit defense that permitted the Saints’ lead wide receiver, Chris Olave, to explode for 182 yards in the opener.
Jared Goff Over 268.5 passing yards (-113 via DraftKings)
Buffalo’s defense isn’t actually an impenetrable fortress through the air, either. CJ Stroud was embattled throughout the 2025 season, but he had little trouble producing 274 passing yards against the Bills in Week 1.
To keep pace with the scoring output I’m expecting from the Bills, Goff should take to the air with frequency for four quarters.
🎟️ Most-bet Lions vs. Bills player props
Betting insights via BetMGM.
| Player | Team | Bet | Odds |
|---|---|---|---|
| DJ Moore | Bills | Over 61.5 receiving yards | -125 |
| Dalton Kincaid | Bills | Over 50.5 receiving yards | -135 |
| Josh Allen | Bills | Over 31.5 rushing yards | -115 |
| Jameson Williams | Lions | Over 56.5 receiving yards | -125 |
| Keon Coleman | Bills | Over 13.5 receiving yards | -135 |
📺 How to watch Lions vs. Bills: Week 2
- Date: Thursday, Sept. 17
- Kickoff: 8:15 p.m. ET
- Location: Highmark Stadium (Orchard Park, N.Y.)
- Streaming: Prime Video
Related Articles
