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College Football Week 3 Predictions 2023: Picks & Odds for Marquee Games

Esten McLaren

Last Updated: September 16, 2023 3:37 PM EDT • 2 min 25 sec read.

Head coach Deion Sanders of the Colorado Buffaloes points to the crowd as we look at our best college football Week 2 predictions
Head coach Deion Sanders of the Colorado Buffaloes points to the crowd before a game against the Nebraska Cornhuskers at Folsom Field on September 9, 2023 in Boulder, Colorado. Photo by Dustin Bradford/Getty Images via AFP.

College football's Week 3 rolls into the Saturday slate, highlighted by the late-night matchup between Colorado State and Colorado as our college football picks and predictions for Week 3 look for value from our best college football betting sites.

The five college football games split between Thursday and Friday served only as the appetizer to Saturday's full slate and the battle between Colorado State and Colorado as Deion Sanders' upstart outfit continues to take the nation by storm after rising to No. 18 in the latest AP top 25 poll.

Our hunt for the best Colorado State vs. Colorado odds has helped bridge the gap from Saturday to Saturday as we look at all of our top college football Week 3 predictions to help with your college football best bets for Week 3.

College football picks and predictions for Week 3

College football predictions for Saturday

Tennessee vs. Florida +6.5 pick: (-104 via FanDuel) ⭐⭐⭐⭐

Pick made by Phil Wood

Syracuse -2.5 vs. Purdue pick: (-105 via FanDuel) ⭐⭐⭐

Pick made by Brenden Schaeffer

Pittsburgh vs. West Virginia Over 47 pick: (-110 via Caesars, bet365) ⭐⭐⭐⭐

Pick made by Brenden Schaeffer

Wyoming vs. Texas pick: Quinn Ewers Under 0.5 interceptions (-145 via bet365) ⭐⭐⭐⭐

Pick made by Shane Jackson

TCU vs. Houston Over 63.5 pick (-115 via FanDuel) ⭐⭐⭐⭐

Pick made by Brenden Schaeffer

Colorado State vs. Colorado pick: Dylan Edwards Over 0.5 receiving touchdowns (+320 via DraftKings) ⭐⭐⭐⭐

Pick made by Shane Jackson; see also Shane's Shedeur Sanders player prop predictions

UTEP vs. Arizona -17 pick (-113 via BetRivers) ⭐⭐⭐⭐

Pick made by Mike Spector

College football expert picks for Week 3

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College football odds pages

CFP National Championship OddsSEC OddsBig 12 Odds
Heisman Trophy OddsBig Ten OddsPac-12 Odds
College Football Playoff OddsMountain West OddsACC Odds

Here are our best college football betting sites:

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

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Written By:
Esten McLaren
Esten is the Senior Publishing Editor for SportsbookReview.com. He previously spent time as the Managing Editor of SportsbookWire.com, and he has done freelance work in sports betting for TheLines, PlayPicks, and BettingPros. He's well versed in the NFL, NHL, MLB, and NBA, but his true passion is with the PGA Tour. Esten's always happy to chase a long shot and will never shy away from a futures bet, but he'll never stop backing Rory McIlroy in majors. He's also a recovering Ottawa Senators and Atlanta Falcons fan. Always bet against the Toronto Maple Leafs at plus money.