Top Serie A Matchday 10 Betting Picks

AC Milan, Inter Milan and Napoli all feature in our top picks for Serie A's Matchday 10.

Soccer fans can look forward to a full slate of Serie A games from Tuesday to Thursday this week. Clubs with larger squads could enjoy an advantage, as their managers will be able to rotate players during this busy period in the calendar.

For that reason, AC Milan, Inter Milan, and Napoli all have a great chance of securing midweek victories.

Here are my top betting picks and predictions for the Serie A Matchday 10 schedule (odds via Unibet; pick confidence based on a 1-to-5-star scale).

Serie A Matchday 10 Picks

AC Milan to win and over 1.5 goals (-122) (????)Inter Milan -1.25 Asian handicap (+102) (???)Napoli win to nil (+155) (??)

SEE ALSO: Top La Liga Matchday 11 betting picks

Serie A Matchday 10 Predictions

AC Milan to win and Over 1.5 goals (-122)

AC Milan moved level with Napoli at the top of the table after thrashing Bologna 4-2 on Saturday. It is missing several key players due to injury right now, but manager Stefano Pioli was still able to rotate his forwards effectively.

M Rafael Leão and F Zlatan Ibrahimovi? were both on target in the win, and M Alexis Saelemaekers impressed in a brief cameo.

Milan now has eight wins and a draw through nine Serie A games this season. It will bid to extend its unbeaten run to 10 games when it hosts Torino at the San Siro on Tuesday.

The Rossoneri have a 100 percent home record in Serie A play, and they are currently on a five-game winning streak in the league. They should approach this game with a great deal of confidence. It is also worth noting that they beat Torino 2-0 at home and 7-0 on the road last season. 

Torino welcomed captain Andrea Belotti back from injury in a 3-2 win against Genoa on Friday. It could cause Milan’s defense problems in this game, but Pioli’s men should wrap up a comfortable victory.

Inter Milan -1.25 Asian handicap (+100)

Inter will be desperate to return to winning ways when it takes on newly promoted Empoli at Stadio Carlo Castellani on Wednesday.

The Nerazzurri came within an inch of beating Juventus on Sunday, but D Denzel Dumfries conceded a late penalty, allowing Juventus to snatch an undeserved 1-1 draw.

That result leaves Inter seven points behind Napoli and AC Milan at the top of the table. It needs to bounce back with a win, and Empoli should prove to be an obliging opponent.

Manager Aurelio Andreazzoli’s team has made an encouraging start to life in Serie A. A 4-2 win against Salernitana Calcio on Saturday carried it up to 10th in the table, with four wins and five defeats through nine games.

However, Empoli struggles in defense. It has conceded 10 goals in its last four games, which does not bode well for a game against Inter, which is the top-scoring team in Serie A this season.

Inter has a much deeper squad than Empoli, which should allow it to secure an emphatic away win on Wednesday.

Napoli win to nil (+155)

Bologna will be missing playmaker M Roberto Soriano and D Adama Soumaoro for this game after both men were sent off in Saturday’s 4-2 defeat to Milan.

Manager Siniša Mihajlovi?’s squad failed to score in only one of their nine games so far this season, but that came when Soriano was sidelined. He is the creative spark for this team, so his absence could leave Bologna a little toothless in attack.

Napoli has the best defensive record in Serie A, with just three goals conceded through nine games. It has kept six clean sheets in Serie A play, and it has conceded only one goal across four home matches.

Bologna has a miserable 0-2-2 away record, so Napoli should be able to grind out a low-scoring win in this match. If you want to be more cautious, you could go for Napoli to win and Under 4.5 goals, or Napoli -1 Asian handicap, but the odds on Napoli to win to nil look very appealing.

Serie A Matchday 10 Quick Picks

Lazio vs. Fiorentina: Both teams to score and Over 2.5 goals (-109) | Both teams to score has paid off in seven of Lazio’s nine games this season, and its matches average four goals, so its game with Fiorentina should be a high-scoring clash.AC Milan vs. Torino: Milan and Over 1.5 goals (-122) | Milan should have enough attacking quality to outgun an improving Torino side in this match.Empoli vs. Inter Milan: Inter -1.25 Asian handicap (+102) | Inter is the top-scoring team in Serie A this season, and Empoli has a very leaky defense, so Inter should be able to win this game by two or more goals.Napoli vs. Bologna: Napoli win to Nil (+155) | Napoli has conceded only one goal in four home games this season, and Bologna will be missing key playmaker Soriano.

SEE ALSO: All of our soccer picks and predictions

Picks made 10/25/2021 at 10:30 a.m. ET.