Cowboys vs. Colts Prediction: Week 9 Odds, Picks & Best Bet (Nov. 8)
Last Updated: November 7, 2026 10:30 AM EST • 2 minute read Google News Link
The Cowboys look to put last week's shocking loss to the Cardinals behind them Sunday as I provide my Cowboys vs. Colts prediction and best bets.
Kickoff from Lucas Oil Stadium in Indianapolis is set for 1 p.m. ET (FOX). The Cowboys are priced as a 5.5-point betting favorite, while the 51.5-point total is one of the highest of the Week 9 slate.
Cowboys vs. Colts picks & predictions
See all of our experts' NFL picks for Week 9 based on the latest NFL odds.
| Pick | Odds | Bet size |
|---|---|---|
| Cowboys -5.5 | -110 via BetMGM | 0.5 units to profit 0.46 units |
| Over 51.5 | -108 via BetMGM | 1 unit to profit 0.93 units |
Picks submitted: Nov. 4 at 1 p.m. ET. Odds subject to change.
Total wagered: 1.5 units | Max profit: +1.39 units
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Cowboys vs. Colts prediction & best bet
Over 51.5 (-108 via BetMGM)
The Cowboys are an Over bettor's dream: the Over has hit in three of four Dallas games with a total above 50 points this season. Luckily for the Cowboys, theirs isn't the only poor defense in this matchup.
Two toothless defenses should lead to plenty of scoring between the Cowboys and Colts, who both rank bottom-six in the league in points against.
The best sports betting sites are aligned on a 51.5-point total, with BetMGM offering the top value on the Over at -108 odds. However, I would play this bet to -116.
📡 SBR Edge
Cowboys games have averaged 56.56 total points since the start of last season.
Cowboys' defense out of answers
The Cowboys' defense remains a horrendous unit even after the team made major investments in it, hired a new defensive coordinator, and then brought in an experienced NFL coach to help out the DC.
As bad as Daniel Jones has played lately, there is literally no better defense for him to move the ball against than a Dallas unit that ranks last in EPA/play allowed. The Cowboys have more firepower to win this game, but the Colts will do some damage as well.
Play to: 52.5 (-104), pass at 53.5.
Score prediction: Cowboys 30, Colts 23
Live Cowboys vs. Colts odds
See the latest odds movement and more on our Cowboys vs. Colts page.
Cowboys vs. Colts opening odds
- Moneyline: Cowboys -228 | Colts +182
- Spread: Cowboys -4.5 (-110) | Colts +4.5 (-110)
- Over/Under: Over 51.5 (-110) | Under 51.5 (-110)
Cowboys vs. Colts weather
Indianapolis' Lucas Oil Stadium is an indoor domed environment, so weather won't be a factor in this matchup.
Latest Cowboys vs. Colts injuries
How to watch Cowboys vs. Colts: Week 9
- Date: Sunday, Nov. 8
- Kickoff: 1 p.m. ET
- Location: Lucas Oil Stadium (Indianapolis)
- TV/Streaming: FOX
Liam Fox