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Christian McCaffrey Player Prop Picks for Monday Night Football: Will Star 49ers RB Shine in Primetime?

How will the newest addition to the San Francisco 49ers backfield do under the bright lights in Mexico City? Let’s take a look with our Monday Night Football prop picks for Christian McCaffrey.
Rodrigo Villagomez
Rodrigo Villagomez

Last Updated: September 11, 2024 2:44 PM EDT • 3 minute read

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How will the newest addition to the San Francisco 49ers' backfield do under the bright lights in Mexico City? Let’s take a look at our top Christian McCaffrey player prop picks for Monday Night Football. 

The San Francisco 49ers have shown a little more jump since running back Christian McCaffrey’s return to the Bay Area. He’s made an immediate impact in not just the running game, but has contributed with his receptions as well. On top of that, CMC has thrown a touchdown pass in his time with the Niners.

Here are our top player props and predictions for Christian McCaffrey on Monday Night Football (odds via Barstool Sportsbook and Caesars Sportsbook).

Check out our 49ers vs. Cardinals picks and our top Monday Night Football props.

49ers vs. Cardinals Odds

Christian McCaffrey Player Prop Picks

Mc Caffrey 1121

Christian McCaffrey Player Prop Predictions 

McCaffrey Over 103.5 rush and receiving yards (-115)

This will be McCaffrey’s second meeting against Arizona this season, having met back in Week 4 when he was with the Panthers. CMC gained 108 total yards against the Cardinals during that game. McCaffrey rushed for just 27 yards on nine carries, but caught all nine of his targets for 81 yards. The star back has gone Over this total six times this season, including once with his new team. 

Barstool offers the best value on the market for this prop. Most books are offering this line at 106.5, with DraftKings giving you -115 for the three extra yards. BetMGM also tacks on the three yards, but at least drops the odds to -110, while Caesars dips even lower giving you -106 for the higher threshold. 

McCaffrey Over 4.5 receptions (-127)

Four of McCaffrey’s last six games have seen him eclipse this receptions mark. Granted, only one has occurred since joining Deebo Samuel and George Kittle in San Francisco. However, he has enjoyed plenty of success against the Cardinals in his career. In his three games against Arizona, CMC has caught 22 passes and has cleared this prop twice. 

Last season, San Francisco running back Elijah Mitchell snared all five of his targets against the Cardinals. This line is constant across the books, but the price varies slightly with Caesars ultimately giving you the best odds.

McCaffrey longest rush Under 16.5 yards (-125)

Since joining the 49ers, McCaffrey has had only one rush longer than this distance. He has recorded a long run of 12 yards on two different plays. He has had five games in which he has eclipsed this mark, however, his longest burst was just 10 yards in his last outing against the Cardinals. 

Arizona is giving up an average of 4.4 yards per carry to opposing running backs so far this season. McCaffrey has had one single running play go Over this mark against the Cardinals, notching a 76-yard carry against them in 2019. 

Where to Bet on Christian McCaffrey Prop Picks

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Christian McCaffrey prop picks made 11/21/2022 at 11 a.m. ET

Written by:
Rodrigo Villagomez
Rod has been a contributing author at Sportsbook Review for the last two years specializing in NASCAR and NFL prop betting. He has been writing and podcasting professionally for almost 20 years, spending the last four years in the sports gambling space. Rod has made several appearances on the SiriusXM Fantasy Sports channel. He’s appeared multiple times on the Fantasy Alarm Show with Howard Bender as well as several times over the last two years during the FSGA Draft Week. He is a published author in the academic world with an article on steroids in baseball featured in the Bedford Reader textbook. Rod loves to find non-traditional bets which has led him to dive into the world of defensive and kicking props in football among others. His love of motorsports has translated into several winning weeks of both NASCAR and Formula 1 bets. Rod is a fan first and aims to provide betting picks that are not only profitable but will provide the maximum entertainment value during the sweat. Ultimately, he tries to remember that watching sports should still be fun and anything else is icing on the cake.