Monday Night Football Prop Picks, Predictions Week 11: 49ers Meet Cardinals in Mexico City
The San Francisco 49ers and Arizona Cardinals clash in a divisional battle in Mexico City. Find out our favorite betting angles with these Monday Night Football prop picks for the 49ers and Cardinals.
Once again the NFL travels outside the United States for this NFC West showdown. The 49ers and Cardinals will compete in the Estadio Azteca in Mexico City Monday night. San Francisco is looking to pull even with the Seattle Seahawks for first place in the NFC West. Arizona is hoping not to fall too far back in the race to the top.
Here are our top Monday Night Football prop picks for Week 11 (odds via DraftKings Sportsbook, FanDuel Sportsbook, and Barstool Sportsbook).
Check out 49ers vs. Cardinals picks and preview.
49ers vs. Cardinals Odds
Monday Night Football Prop Picks: 49ers vs. Cardinals
49ers vs. Cardinals Prop Predictions for Monday Night Football
Total touchdown yards Under 72.5 (-110)
San Francisco has crossed the goal line 23 times this season. The distance covered by all of these scoring plays combined is 353 yards. The 49ers average 39.2 total touchdown yards per game. They also are averaging 15.3 yards per touchdown scored this season. Defensively, they are surrendering an average of 37.1 total touchdown yards in each contest, and the Niners have combined with their opponent to top this mark in only four matchups this year.
Arizona has 27 six-point plays in its 2022 campaign. On average, the Cardinals have accumulated 38.2 total touchdown yards per game and average 14.1 yards per touchdown. Opponents have scored 30 touchdowns against the Cards at a total of 253 yards on those plays. Through 10 games, that is an average of 25.3 total touchdown yards per contest. Arizona has also hit this mark in four games this season.
Fourth quarter total Under 12 (-112)
The 49ers enter this week averaging seven points in the final frame of their games. Five of their nine games hit the Under on this prop including two of their three NFC West tilts. Overall, San Francisco scores 22.0 points per content. Only 9.6 of those occur in the final 15 minutes.
The Cardinals fare somewhat better in the last frame of their games, averaging 8.3 points per fourth quarter. They too have participated in five games this season that failed to eclipse 12 points in the final stanza. Arizona is a better second-half team, improving from 9.1 points in the first half to 13.3 after halftime.
Fourth-quarter scoring wouldn't have cashed the Over on this line in three of the last four head-to-head meetings.
First to 30 points: Draw (-155)
San Francisco reached 30 points only twice this season, in Week 5 against the Carolina Panthers and again in Week 8 against the Los Angeles Rams. The 49ers' defense is allowing the sixth-fewest points per game to their opponents at 18.1. The Niners have allowed just 30 total points in their three NFC West matchups.
Arizona has averaged 23.0 points per game through 10 contests. The Cardinals exceeded this threshold only once this year by scoring 42 points in their Week 7 game against the New Orleans Saints. The Cards are in the bottom five of the league while allowing 25.8 points per game to their opposition and Arizona has allowed four teams to cross this mark against them this year.
Where to bet on 49ers vs. Cardinals Prop Picks
49ers-Cardinals prop picks made 11/21/2022 at 9:52 a.m. ET.
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