White Sox vs. Guardians Prediction & Picks: MLB Odds for Monday, Sept. 14
The White Sox and Guardians are battling for first place in the AL Central, and my White Sox vs. Guardians prediction expects Cleveland to overtake Chicago in the standings today.
Sean Newcomb will serve as the opener for the White Sox, with Sean Burke likely pitching in bulk relief, while the Guardians will start Gavin Williams. My MLB picks back the Guardians as a -148 betting favorite, with first pitch from Progressive Field in Cleveland set for 6:40 p.m. ET (ESPN Unlimited, MLB.TV).
βΎ White Sox vs. Guardians picks & odds today
See all of our expertsβ MLB picks based on the latest MLB odds.
| βΎ Pick | π΅ Units | π Notes |
|---|---|---|
| Guardians ML (-148 via FanDuel) | 2.22u β 1.5u | The Guardians are 4-0 in Williams' last 4 starts, with the RHP allowing 2 or fewer ER 3 times in that span. |
| Chase Meidroth Under 0.5 singles (-137 via DraftKings) | 1.37u β 1u | Meidroth is slashing just .246/.318/.342 vs. RHP. |
Total wagered: 3.59 units | Max profit: 2.5 units
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π° White Sox vs. Guardians prediction & best bet
Follow all of our MLB analysis and expert predictions for baseball season.
Guardians ML (-148)
The Guardians can move into first place in the AL Central with a win today, and they're in a solid spot with their starting pitcher. Williams has allowed two or fewer earned runs in three of his last four starts, with the Guardians going 4-0 in that span.
Not only has he had success recently, but he's also been dominant against the White Sox. Current White Sox hitters are slashing just .219/.296/.329 against Williams across 73 career at-bats. Guardians ML (-148) at FanDuel is the best line available among the top MLB betting sites.
💵 More MLB expert picks today
Looking for more? Dive into Mike Spector's best NRFI bets today.
π₯ Best White Sox vs. Guardians player prop bet
Chase Meidroth Under 0.5 singles (-137)
Not only has Chase Meidroth not recorded a single in any of his last three games, but he's also struggled against right-handed pitching this season.
The White Sox second baseman is slashing just .246/.318/.342 against right-handed pitchers, much lower than his .324/.414/.554 slash line against lefties.
With Meidroth exclusively hitting for power lately - and struggling against righties on the season - his odds of hitting a single are much lower than these odds suggest. Meidroth Under 0.5 singles (-137) at DraftKings is the best line available among the top sports betting sites.
📡 SBR Edge: Breaking Balls from Righties
Williams throws 51.9% breaking balls to right-handed batters, and Meidroth has just a .166 expected batting average against breaking balls from right-handed pitchers.
π Live White Sox vs. Guardians odds
π White Sox vs. Guardians injuries
πΊ How to watch White Sox vs. Guardians
- Date: Monday, Sept. 14
- First pitch: 6:40 p.m. ET
- Ballpark: Progressive Field (Cleveland)
- TV: ESPN Unlimited, MLB.TV
- White Sox opener: Sean Newcomb (2-4, 2.77 ERA)
- Guardians starter: Gavin Williams (13-7, 3.78 ERA)
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