Louisville vs. Coastal Carolina Prediction, Picks & Odds Today: College World Series Preview & Best Bets

Last Updated: June 18, 2025 8:47 AM EDT • 4 minute read X Social Google News Link

One of No. 13 Coastal Carolina (55-11) and Louisville (38-21) will advance to the Finals, and the favored Chanticleers have two games to do it due to college baseball’s double-elimination format. Let’s dive into the Louisville vs. Coastal Carolina prediction and odds – Coastal is now just +200 to win it all, per the College World Series odds.
🔮 Louisville vs. Coastal Carolina prediction & picks
Coastal enters this game on an unbelievable 25-game winning streak that dates back to mid-April. The Chants’ two victories at the tournament saw them conserve much of their bullpen while getting solid outings from their three weekend starters, one of whom entered in relief.
On the other side, Louisville had to play an elimination game yesterday and used six different pitchers, three of whom tossed over 20 pitches. The team’s three relievers with three or more saves, Tucker Biven (3.71 ERA, 4 SV), Jake Schweitzer (2.25 ERA, 3 SV), and Wyatt Danilowicz (2.70 ERA, 3 SV), have tossed 145 balls in Omaha.
It’s a lopsided pitching matchup in Coastal’s favor.

🆚 Who will win Louisville vs. Coastal Carolina?
It was a good run, Louisville. The Cardinals just don’t have the depth necessary to top the Chants today. When penciling in a starting pitcher, head coach Dan McDonnell likely must go with someone we haven’t seen him use in the tournament. He also doesn’t have fresh enough quality arms for a bullpen game with Bivens up to 74 pitches since Sunday. Peter Michael (4-3, 4.52 ERA) is an option, albeit an uninspiring one relative to Coastal’s weapons.
The Chants do not have this problem. Coastal Carolina won’t have its best pitcher, Jacob Morrison (12-0, 2.08 ERA), who threw 109 pitches on Sunday, but weekend starter Riley Eikhoff (6,-2, 2.98 ERA) could be in the mix after tossing just 45 last Friday. Weekday starter Luke Jones (4-2, 3.51 ERA) hasn’t pitched yet, and relievers Ryan Lynch (0.58 ERA, 9 SV) and Dominick Carbone (2.61 ERA, 5 SV) are fresh.
Omaha’s Charles Schwab Field is a pitcher’s park. I trust a rested Coastal team and its 3.23 team ERA versus a Louisville team that played yesterday and sports a 5.29 team ERA. Our best sports betting sites list Coastal as an overwhelming favorite for a reason.
✅ Run line pick: Coastal -1.5 ⭐⭐⭐⭐⭐
📊 Best odds: -130 via Caesars ($10 to win $7.69)
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🎯 Exact score prediction: Coastal 6, Louisville 1 (+4000) ⭐⭐
The Louisville pitching staff will struggle to keep Coastal off the board, but the Chants aren’t a home-run heavy team, and Charles Schwab isn’t a home-run friendly ballpark. While I don’t expect Coastal to produce eye-popping offensive numbers, they’ll get the best of a tired bullpen.
Louisville’s .899 team OPS edges Coastal’s .850 team OPS slightly, and I think they’ll plate at least a run despite the tricky pitching matchup.
📊 Best odds: +4500 via DraftKings ($10 to win $450)
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📊 Louisville vs. Coastal Carolina betting odds
Here are the latest Louisville vs. Coastal Carolina odds courtesy of DraftKings as of Wednesday morning.
💰 Moneyline
- Coastal Carolina: -238
- Louisville: +180
💰 Run line
- Coastal Carolina: -2.5 (+110)
- Louisville: +2.5 (-175)
💰 Over/Under
- Over 11 (-115)
- Under 11 (-115)
📺 How to watch Louisville vs. Coastal Carolina tonight
📅 Date: Wednesday, June 18
🕒 Start time: 2 p.m. ET
📍 Location: Charles Schwab Field (Omaha, Neb.)
📺 TV: ESPN
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