Best NRFI Bets Today: MLB No Run First Inning Picks for Monday, Sept. 21

My best NRFI bets today break down the top no run first inning picks across Monday's MLB slate with pitcher matchup analysis for each game.
Toronto Blue Jays starting pitcher Trey Yesavage delivers a pitch as we make our best NRFI picks today
Pictured: Toronto Blue Jays starting pitcher Trey Yesavage delivers a pitch as we make our best NRFI picks today. Photo by Troy Taormina-Imagn Images
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My NRFI picks are 6-2 over the last two days, and my best NRFI bets today look to continue that momentum amid Monday’s small three-game MLB slate.

Trey Yesavage makes his first start for the Toronto Blue Jays since Aug. 4, and I expect him to match zeros with Baltimore Orioles righty Shane Baz. I also look at the Twins-Giants interleague matchup with the second of my two NRFI wagers.


⚾ Best NRFI bets today: Sept. 21

See all of our experts’ MLB picks based on the latest MLB odds.

⚾ NRFI pick 💵 Units 📝 Notes
Blue Jays vs. Orioles NRFI (-125 via bet365) 1u → 0.80u Baz has held current Blue Jays batters to a combined .219 OBA
Twins vs. Giants NRFI (-114 via Caesars) 1u → 0.88u Hitter friendly Oracle Park should limit both teams’ bats early

Total wagered: 2 units | Max profit: 1.68 units

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💰 Best NRFI bet today

Blue Jays vs. Orioles (6:35 p.m. ET)

  • Trey Yesavage (3.65 ERA) vs. Shane Baz (4.11 ERA)
  • NRFI records: Blue Jays (78-79) vs. Angels (87-69)

Shane Baz has solid career numbers against current Blue Jays batters, holding them to a combined .219/.260/.280 slash line over 73 at-bats. Perhaps the most impressive part is that just three of his 16 hits allowed have gone for extra bases, with one home run.

Trey Yesavage had made quality starts in four of six outings prior to his injury. It is somewhat concerning that his average fastball velocity sat at 93.3 mph in his last rehab outing of 34 pitches. But he allowed just two hits over five innings in his only road start at the Orioles this year, and I expect much better control than his seven walks.

📡 SBR Edge: An NRFI bettor's dream

Baltimore is the AL's second-most profitable NRFI team this season.


🔥 NRFI picks today

Twins vs. Giants (6:40 ET)

  • Zebby Matthews (4.74 ERA) vs. Blade Tidwell (4.56 ERA)
  • YRFI records: Dodgers (74-75) vs. Reds (80-69)

Minnesota is MLB’s second-most profitable YRFI team, and has cashed it in two-thirds of its road games. But a chilly night in Oracle Park should limit offense early.

Zebby Matthews is coming off arguably his best start of the season, holding the Yankees scoreless over six innings while allowing just two hits. The Tigers and White Sox tagged Matthews for nine earned runs in 7.1 innings prior to that start, but Matthews has been great against non-divisional rivals. Before facing the Yankees, he allowed two earned runs with an 11:2 K:BB ratio in his previous two starts against teams outside the AL Central (spanning 12.2 innings).

Blade Tidwell has pitched better than his 4.60 ERA in September suggests, as he has allowed a .182 OBA in 15.2 innings.


🚀 Best NRFI parlay today

There are not many options to choose from with Major League Baseball having just three games on today’s slate. But between Shane Baz’s excellent career numbers against Toronto and Zebby Matthews' run of solid starts against teams outside the AL Central, I feel confident about my two NRFI plays and subsequent SGP.

💵 Best NRFI parlay today

  • Blue Jays-Orioles NRFI
  • Twins-Giants YRFI

Best odds: +237 via bet365 (0.1u -> 0.24u)


❓ NRFI betting FAQ

What does NRFI mean in baseball betting?

NRFI stands for "No Run First Inning." It's a popular MLB bet that neither team will score in the first inning of a game, and the bet settles after just six outs (three per half-inning).

What does YRFI mean?

YRFI stands for "Yes Run First Inning" - the opposite of an NRFI. This MLB prop bet cashes if there's at least one run by either team in the first inning.

What should I look for when betting NRFIs?

Each team's starting pitcher is the biggest factor in cashing a NRFI bet, but you should also focus on each team's NRFI records (home vs. away) and each lineup's first-inning tendencies. Recent form can also play a bigger role than full-season numbers.