Clemson vs. California Prediction: Week 4 Odds, Picks & Best Bet
Last Updated: September 25, 2026 4:01 AM EDT • 2 minute read X Social Google News Link
My best Clemson vs. California prediction focuses on both teams' offensive struggles this season. While both rush defenses have been really bad, I don't think that either offense has the ground game to move the ball with any type of consistency and put points on the board.
Clemson is favored by 1.5 points ahead of tonight's 10:30 p.m. ET game at California Memorial Stadium in Berkeley, Calif. The game will air on ESPN and stream on ESPN Unlimited.
🏈 Clemson vs. California picks & predictions
See all of our experts' college football picks for Week 4 based on the latest college football odds.
| Pick | Bet size |
|---|---|
| ATS: California +1.5 (-115 via FanDuel) | 1.5 units to win 1.3 units |
| O/U: Under 50.5 (-110 via FanDuel) | 2 units to win 1.82 units |
Total wagered: 3.5 units | Max profit: 3.12 units
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💰 Clemson vs. California prediction & best bet
Check out all of our college football predictions for more analysis across this week's slate.
Under 50.5 (-110 via FanDuel)
Clemson has scored just 60 points this season, averaging 20 points per game. Last weekend, the Tigers scored 28 points, but 14 of them came in the final 5:01 of the game. Freshman Tait Reynolds is expected to be under center again, and he's been far from convincing this season, throwing an interception last week and completing just 59.3% of his passes against Georgia Southern.
California's offense has struggled this season as well. The team has managed just 45 points against FBS opponents, scoring 21 against Syracuse and 24 against UCLA. Even with a 49-point performance against Wagner, California ranks 72nd in the nation in points per game.
📡 SBR Edge: Tigers' offensive struggles
Clemson's 4.75 yards per play ranks 126th in the country. If you think the game against LSU is making Clemson's offense look worse than it is, think again. Clemson averaged just 4.68 yards per play against Georgia Southern.
Neither offense can exploit weak rush defenses
Clemson is allowing 181.7 rushing yards per game, which ranks 119th, while California is barely better, allowing 169 per game, ranking 110th. When it comes to yards allowed per carry, both teams rank 111th or worse, but California has been particularly bad, ranking 129th and allowing 5.34 yards per rush.
However, both of these rushing attacks are among the worst in the nation. Clemson ranks 109th in rushing yards per game, while California ranks 126th. Both teams are averaging 3.72 yards per carry or less. With neither offense able to take advantage of the other team's obvious weakness, I don't anticipate a lot of scoring.
Score prediction: California 21 Clemson 18
📊 Live Clemson vs. California odds
See the latest college football odds for every Week 4 matchup.
Clemson vs. California opening odds
- Moneyline: Clemson -112 | California -104
- Spread: Clemson -1.5 (-105) | California +1.5 (-115)
- Over/Under: Over 47.5 (-110) | Under 47.5 (-110)
📺 How to watch Clemson vs. California: Week 4
- Date: Friday, Sept. 25
- Kickoff: 10:30 p.m. ET
- Location: California Memorial Stadium (Berkeley, Calif.)
- TV: ESPN
- Streaming: ESPN Unlimited
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Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
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