USA vs. Peru Prediction, Picks & Odds for Saturday's Friendly

My USA vs. Peru prediction breaks down a friendly on Saturday in Orlando at Inter.co Stadium.
Pictured: USMNT midfielder Tyler Adams in action as we break down our USA vs. Peru Prediction, Picks & Odds. Photo by IMAGN IMAGES via Reuters/David Gonzales.
Pictured: USMNT midfielder Tyler Adams in action as we break down our USA vs. Peru Prediction, Picks & Odds. Photo by IMAGN IMAGES via Reuters/David Gonzales.
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The United States are back in action on Saturday for the first time since their heartbreaking Round of 16 exit at the hands of Belgium this past summer, and my USA vs Peru prediction is expecting the hosts to take advantage of a vulnerable Peruvian backline. 

Kickoff from Inter.co Stadium in Orlando is scheduled for 4:30 p.m. ET, with coverage available on TNT, and HBO Max for streaming. 


⚽ USA vs. Peru predictions & best bets

See our experts' soccer picks.

Best bets Best odds Wager (units)
USA Over 1.5 goals -169 at DraftKings 0.5 units
Damion Downs anytime goal +135 at DraftKings 0.25 units

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💰 Our USA vs. Peru best bet

Check out all of our soccer betting analysis and expert predictions this season.

USA Over 1.5 total goals (-169 at DraftKings)

This USMNT squad has a much different look right now. Mauricio Pochettino selected 13 uncapped players, and the likes of Christian Pulisic, Tim Ream, Weston McKennie, and Folarin Balogun, among others, weren't included. Pochettino is looking to evaluate young talent. 

Regardless, I expect the Americans to score goals on Saturday. They've won three straight games against teams ranked outside of the top-30, scoring a minimum of two goals in each match. 

Peru is also very shaky at the back. The visitors have conceded at least twice in four of their previous six outings. 

The youthful talent in this squad will prove its worth against the South Americans. 

🆚 Who will win USA vs Peru?

It's certainly hard to know what to expect from the United States when a lot of this team wasn't playing in the World Cup, but there is some very intriguing talent at Pochettino's disposal. The hosts will secure a convincing victory. 

Score prediction: USA 3, Peru 1


🔥 More USA vs. Peru expert picks

Damion Downs anytime goal (+135 at DraftKings)

With Ricardo Pepi withdrawing due to injury, Damion Downs suddenly has a real opportunity to lead the line for the United States. The St. Louis City SC forward has six USMNT appearances to his name and converted the winning penalty in the 2025 Gold Cup quarterfinal shootout against Costa Rica.

Downs hasn’t produced much since joining St. Louis on loan from Southampton, but he does have considerably more senior international experience than the other forwards in this camp. Cole Campbell, Justin Ellis, Julian Hall and Cavan Sullivan are all still uncapped, making Downs the most obvious candidate to start centrally against Peru.

He’s still searching for his first USMNT goal, but this is exactly the type of opportunity he needs. Against a Peru side the Americans are expected to control for long stretches, Downs should get chances in and around the penalty area.


📊 USA vs. Peru odds

Odds from DraftKings as of Sept. 25; subject to change

  • Three-way moneyline: USA (-195) | Draw (+330) | Peru (+475)
  • Total: Over 2.5 (-130) | Under 2.5 (-110)

🆚 USA vs. Peru projected lineups

Here are the projected lineups for USA vs. Peru; subject to change:

USA (4-2-3-1) Peru (4-3-3)
Freese (GK) Gallese (GK)
Freeman (D) Sonne (D)
Trusty (D) Garcés (D)
Richards (D) Araujo (D)
Robinson (D) López (D)
Adams (M) Cartagena (M)
Berhalter (M) Yotún (M)
Dest (D) Vélez (M)
Tillman (M) Magallanes (F)
Reyna (M) Valera (F)
Downs (F) Lapadula (F)

📺 How to watch USA vs. Peru

  • Date: Sept. 26, 2026
  • Kickoff: 4:30 p.m. ET
  • Location: Inter.co Stadium (Orlando)
  • TV/Streaming: TNT/HBO Max