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Premier League Best Bets for Matchday 2: Matchups, Odds, Picks, and Predictions

Premier League Best Bets for Matchday 2: Matchups, Odds, Picks, and Predictions
Leicester City forward Jamie Vardy during the English championship Premier League football match between Leicester City and Brentford on Aug. 7. Photo by Manjit Narotra / ProSportsImages / DPPI via AFP

After the first matchday of the year was full of surprises, here are the best bets for Matchday 2 of Premier League action.

Erling Haaland did indeed headline the first week of Premier League play, as the Striking Viking netted two goals for reigning champs Manchester City. Runner-ups Liverpool didn’t have the same fate, tying Fulham 2-2, but facing Crystal Palace is a new challenge.

Here are our best bets for Matchday 2’s Premier League slate (odds via DraftKings Sportsbook and PointsBet; pick confidence based on a 1-to-5-star scale).

Matchday 2’s Premier League Schedule and Odds

(odds via DraftKings Sportsbook)

  • Aston Villa (-120) vs. Everton (+380)
  • Manchester City (-1400) vs. Bournemouth (+2800)
  • Arsenal (-210) vs. Leicester (+550)
  • Wolves (+135) vs. Fulham (+215)
  • Leeds (+215) vs. Southampton (+130)
  • Brighton (+145) vs. Newcastle (+200)
  • Nottingham Forest (+320) vs. West Ham (-110)
  • Chelsea (+130) vs. Tottenham (+220)
  • Manchester United (+100) vs. Brentford (+290)
  • Liverpool (-500) vs. Crystal Palace (+1400)

Premier League Best Bets

  • Moneyline: Leeds (+215 via DraftKings) ★★★
  • Spread: Newcastle -0.25 (+155 via DraftKings) ★★★★
  • Total: Aston Villa vs. Everton Under 2 goals (+160 via Draftkings) ★★★
  • Upset: Tottenham (+220 via DraftKings) ★★★★
  • Prop bet: Jamie Vardy anytime goalscorer (+250 via DraftKings) ★★★
  • Scorer prop parlay: Kevin De Bruyne to score and assist (+350 via DraftKings) ★★★

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Matchday 2’s Premier League Top Picks

Moneyline: Leeds (+215)

While the odds were stacked against Jesse Marsch’s side heading into Matchday 1, they proved doubters wrong in a come-from-behind win to beat Wolves 2-1.

On the other side, Southampton were battered by Tottenham despite James Ward-Prowse grabbing them an early lead. They conceded four unanswered goals, including an own goal, falling 4-1 to Spurs.

Of course, Spurs are a Champions League side expected to beat a team like Southampton, but with the American coach guiding fellow Americans Tyler Adams and Brenden Aaronson, Leeds got a confidence boost at Elland Road.

Those two along with Rodrigo and Patrick Bamford brought scoring, precise ball movement, and energy to the pitch in the win, and will look to do the same in the Southampton game.

Spread: Newcastle -0.25 (+155)

Brighton started off their season spoiling Erik ten Hag’s arrival at Manchester United, though after their well-documented struggles last season and little transfer activity, it was easy to read that Brighton could easily win the game.

As for Newcastle, who went from teetering relegation to finding solid form at the end of last season, they dominated Nottingham Forest thanks to goals from Callum Wilson and Fabian Schar.

With Bruno Guimaraes playing lights out for the Magpies, and Brighton having to face a team that has much more chemistry than Manchester United currently does, this game is expected to be a lot closer than both of their previous matches.

Total: Aston Villa-Everton Under 2 goals (+160)

Both teams failed to register a goal in their opening matches as Everton fell 1-0 to Chelsea while Aston Villa were upset 2-0 by newly promoted AFC Bournemouth.

Everton have attempted to bolster their defense by signing Conor Coady from Wolves, pairing him with James Tarkowski to keep the Toffees solid at the backline.

As for Villa, they have won just two of their last 12 Premier League games and have lacked any creativity in their play as they failed to find any attack and break Bournemouth’s defense. While they may be able to stop Everton from scoring, they struggled to find the net themselves.

With neither team able to create any power offensively in the first week of play, it won’t magically appear by Matchday 2, and the game is likely to end very low scoring.

Upset: Tottenham (+215)

Chelsea may have gathered three points over Everton, but the quality of their game was less than ideal and a Jorginho penalty kick was the only saving grace from them ending the game in a 0-0 draw.

Meanwhile, Tottenham had a golazo fest against Southampton with goals from Ryan Sessegnon, Eric Dier, and Dejan Kulusevski.

Kulu may have been the pickup that secured Spurs their Champions League spot after a fantastic second half of the 2021-22 season, and there is no sign of him slowing down anytime soon.

Add to that Harry Kane and Son Heung-min impatiently waiting for their first goals of the season, while Chelsea has sold off a striker in Timo Werner. With more goal-scoring ability than they know what to do with, Tottenham should easily beat the Blues.

Prop bet: Vardy anytime goalscorer (+250)

Leicester may not have had the win they were hoping for as they bottled a 2-0 lead over Brentford in a game that resulted in a 2-2 draw, but Vardy is the club’s third top scorer of all time and has history with Arsenal.

Vardy has scored more against the Gunners than any other club, including 11 league goals in 14 games. Only Wayne Rooney has scored more goals against Arsenal with 12.

While Arsenal has re-upped their defense with the signing of Alex Zinchenko, Vardy loves to score against the North London side more than anyone else, and after failing to score in the March matchup between the two teams, Vardy will be looking to strike.

Parlay: De Bruyne to score and assist (+350)

Kevin De Bruyne is a world-class midfielder and tallied 15 goals and eight assists en route to Manchester City’s Premier League title last season. He has already notched an assist this year in his first match against West Ham.

Now, facing Bournemouth, City will be looking to attack early and often after the Cherries showed what they are capable of against Aston Villa.

Haaland is likely to be the centre of attention once again, and while De Bruyne can feed him on a platter to tally an assist just like they did the week prior, De Bruyne has the ability on his own to score. If last year’s title race showed anything, it’s that every goal counts.

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