England vs. Spain Prediction, Picks & Odds for Saturday's Nations League Match
Familiar foes begin their Nations League campaign on Saturday in London, and my England vs Spain predictions are eyeing the World Cup winners to grab three points on the road.
The kickoff is scheduled for 2:45 p.m. ET at Wembley Stadium, and this fixture will air on FOX Sports in the US. Streaming is also available on Fubo.
⚽ England vs. Spain predictions & best bets
See our experts' soccer picks.
| Best bets | Best odds | Wager (units) |
|---|---|---|
| Spain ML | +125 at DraftKings | 0.5 units |
| Morgan Rogers 1+ SOG | -140 at DraftKings | 0.75 units |
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💰 Our England vs. Spain best bet
Check out all of our soccer betting analysis and expert predictions this season.
Spain moneyline (+125 at DraftKings)
Spain were absolutely phenomenal in the World Cup en route to the title, beating Argentina in extra time in the final. La Roja will still be riding the high of winning the most prestigious trophy in international football, and they will also have fond memories of their last meeting with England.
Luis de la Fuente's men beat the Three Lions 2-1 in the Euro 2024 final, and they've now won two of their previous three games against England.
In fact, Spain is riding a 38-match unbeaten run, with their last defeat coming in 2024. Of course, England is a side that has enough quality to change that, but I cannot overlook La Roja's dominance over the last 2+ years.
🆚 Who will win England vs Spain?
I do not expect this to be a lopsided affair. Five of the last six meetings between Spain and England have been decided by one goal or fewer. Spain will find a late winner to secure the victory.
Score prediction: England 1, Spain 2
🔥 More England vs. Spain expert picks
Morgan Rogers 1+ SOG (-140 at DraftKings)
Morgan Rogers is off to a terrific start domestically with Chelsea this season. He's already bagged three goals in five appearances, while also registering five shots on goal.
Rogers is averaging 1.03 shots on target per 90, and although the -140 price isn't particularly appealing, he simply needs to test the goalkeeper once. Given the confidence he's playing with, that looks like a very reachable mark.
The former Aston Villa man is also averaging three shots per game this term with the Blues. Rogers isn't shy about having a go, making his 1+ SOG prop an intriguing option against Spain.
📊 England vs. Spain odds
Odds from DraftKings as of Sept. 25; subject to change
- Three-way moneyline: England (+195) | Draw (+235) | Spain (+125)
- Total: Over 2.5 (-125) | Under 2.5 (-105)
🆚 England vs. Spain projected lineups
Here are the projected lineups for England vs. Spain; subject to change:
| England (4-2-3-1) | Spain (4-2-3-1) |
|---|---|
| Pickford (GK) | Simon (GK) |
| Quansah (D) | Eric Garcia (D) |
| Konsa (D) | Cubarsi (D) |
| Guehi (D) | Laporte (D) |
| O'Reilly (D) | Cucurella (D) |
| Anderson (M) | Rodri (M) |
| Scott (M) | Pedri (M) |
| Saka (F) | Yamal (F) |
| Bellingham (M) | Olmo (M) |
| Gordon (F) | Nico Williams (F) |
| Kane (F) | Oyarzabal (F) |
📺 How to watch England vs. Spain
- Date: Sept. 26, 2026
- Kickoff: 2:45 p.m. ET
- Location: Wembley Stadium (London)
- TV/Streaming: FOX Sports/Fubo
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