⚽ Burnley vs. Manchester City Prediction, Picks & Odds for Wednesday's Premier League Match
Last Updated: April 21, 2026 2:35 PM EDT • 5 minute read Google News Link
Manchester City's late-season sprint for the title continues with one of the most lopsided matchups in the Premier League against relegation-threatened Burnley. Manchester City will be even on points with league leaders Arsenal with a win over the struggling Clarets.
Following City's big victory over Arsenal on Sunday, my Burnley vs. Manchester City prediction breaks down how Wednesday's contest at Turf Moor in Burnley (3 p.m. ET on Peacock+) will end with Pep Guardiola's team (-700 favorites) level on points with the Gunners after thumping +1600 underdogs Burnley.
My Premier League best bets include a City forward who shouldn't have a problem breaking out of his mini slump.
⚽ Burnley vs. Manchester City predictions
See our experts' soccer picks based on the latest Premier League odds.
| Predictions | Best odds | Bet size | Confidence |
|---|---|---|---|
| Manchester City -1.5 | +333 via bet365 | 1 unit -> 3.33 units | ⭐⭐⭐⭐ |
| Over 2.5 | -275 via bet365 | 1.5 units -> 0.6 units | ⭐⭐⭐⭐ |
| Manchester City clean sheet | -138 via bet365 | 1 unit -> 0.72 units | ⭐⭐⭐⭐ |
| Antoine Semenyo anytime goal-scorer | -115 via DraftKings | 1 unit -> 0.87 units | ⭐⭐⭐ |
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💰 Burnley vs. Manchester City best bet
Check out all of our soccer betting analysis and expert predictions this season.
Manchester City -1.5 (+333)
This could get ugly for Burnley. Given how they've steamrolled past opponents this month, Manchester City shouldn't have any issues winning by a multi-goal margin. City have scored 17 times against Burnley in the last four games in all competitions.
City have scored at least two goals in their last 11 games against Burnley while limiting the Clarets to three goals during that stretch. We're expecting more of the same Wednesday in a game where City will be eager to pad their goal differential stats.
Score prediction: Manchester City 4, Burnley 0
🔥 Best Burnley vs. Manchester City prop bet
Manchester City clean sheet (-138)
Like marathon runners who pace themselves, Manchester City have saved their best soccer for when it matters most in the Premier League title race. And while they're firing on all cylinders offensively, City shouldn't have a problem silencing Burnley's inferior attack as they've been equally impressive defensively.
Manchester City's defense has helped them gain on Arsenal, maintaining three clean sheets in their last four games.
City have limited opponents to four goals in the last seven games. Burnley have been held goalless in three of their last five outings. This has Manchester City blowout win written all over it.
🙌 Best Burnley vs. Manchester City goal-scorer prediction
Antoine Semenyo, Manchester City (-115)
The inclusion of Antoine Semenyo in City's lineup should strike fear into Burnley defenders.
The forward has been wildly successful against the Clarets and we're backing him to score against Burnley for the fourth consecutive game.
While Semenyo's direct, high-intensity style has wreaked havoc on Burnley defenders in the past, he could be even more effective in front of goal at Turf Moor. With Erling Haaland set to attract most of the attention, look for Semenyo to exploit the spaces created and benefit from the service of City's creative sparks.
🚀 Burnley vs. Manchester City same-game parlay
This three-game parlay is banking on Manchester City dominating Burnley. We like Manchester City to win by more than a goal based on recent performances against better teams than Burnley. City's defense has been the backbone of their recent run, while Antoine Semenyo has been excellent for City since arriving in January and offers one of the strongest value plays for this contest.
💵 Burnley vs. Manchester City SGP picks
- Manchester City -1.5 (+333)
- Manchester City clean sheet (-138)
- Antoine Semenyo anytime goal-scorer (-115)
Best odds: +1296 via bet365 (1.5 units -> 19.5 units)
⚖️ How I'm handicapping Burnley vs. Manchester City
Based on the form of both teams, we're willing to spend a little more than usual on Manchester City bets. Manchester City rarely struggle against teams battling near the bottom of the table.
Manchester City's desire to improve their goal differential is another deciding factor. As goal differential is the main tiebreaker should City and Arsenal finish level on points, Pep Guardiola's side will probably push for goals right up until the final whistle, regardless if the game is close or not.
Burnley vs. Manchester City key stats
| Burnley | Manchester City | |
|---|---|---|
| Goals for | 34 | 65 |
| Goals against | 67 | 29 |
| Shots on target | 28.35 | 170 |
| xG | 100 | 58.96 |
| Stat X |
📊 Burnley vs. Manchester City odds
[METABET WIDGET -> Game Tile, 350x300 (default)]
Manchester City's win over Arsenal and Burnley's continued struggles have resulted in the odds shifting further in the visitor's direction. After opening as -400 favourites, the odds have plunged to -700 for a Manchester City team aiming to move into first place for the first time since August.
🆚 Burnley vs. Manchester City projected lineups
Here are Wednesday's projected lineups for Burnley vs. Manchester City; lineups subject to change:
| Burnley | Manchester City |
|---|---|
| Dubravka | Donnarumma |
| Walker | Nunes |
| Walker | Khusanov |
| Ekdal | Guehi |
| Hartman | O’Reilly |
| Ward-Prowse | Gonzalez |
| Luis | Silva |
| Ugochukwu | Semenyo |
| Edwards | Cherki |
| Anthony | Doku |
| Flemming | Haaland |
📈 Burnley vs. Manchester City betting trends
| Burnley | Statistic | Manchester City |
|---|---|---|
| 4-8-21 (19th place) | Season record | 20-7-5 (2nd place) |
| 30-25-58 | H2H record | 58-25-30 |
| L-D-L-L-L | Last 5 games | W-D-D-W-W |
| Lost 4-1 vs. Nottingham Forest | Previous result | Won 2-1 vs. Arsenal |
| Burnley have won just one of their last 19 Premier League games against Manchester City. | Key stat | Manchester City have won 14 of their last 15 Premier League games against Burnley. |
Manchester City are firmly in control of the title race after dispatching Arsenal at the Etihad Stadium last weekend. A win over Burnley on Wednesday will only strengthen the club's bid to hoist the Premier League title for the seventh time in nine seasons.
City will be without Ruben Dias and Josko Gvardiol through injury, but their absences shouldn't impact City's approach, as Marc Guehi and Abdukodir Khusanov have played well together at the back.
Burnley are dealing with injuries that could force coach Scott Parker to implement a defensive formation, as Hannibal Mejbri, Zeki Amdouni, and Josh Cullen have been ruled out.
🌤️ Burnley vs. Manchester City weather
It will be mostly cloudy with a low of 37 and a 10% chance of rain in Burnley on Wednesday evening. Overall the conditions favor Manchester City's quick transitioning and short passes, while the wind could make things unpredictable.
📺 How to watch Burnley vs. Manchester City
- Date: Wednesday, April 22
- Kickoff: 3 p.m. ET
- Location: Turf Moor (Burnley)
- TV: Peacock+
❓ Burnley vs. Manchester City FAQ
Who is favored to win Burnley vs. Manchester City?
Manchester City are a -700 betting favorite against Burnley on Wednesday.
Who is the best Burnley vs. Manchester City bet?
The best bets for Burnley vs. Manchester City include Antoine Semenyo to score (-115).
Where to watch Burnley vs. Manchester City in the US and Canada?
You can watch Manchester City vs. Arsenal on Peacock+ in the United States, or stream the game on FuboTV in Canada.
Gordon Brunt