Commanders vs. 49ers Expert Picks for MNF: Monday Night Football Predictions

Our Commanders vs. 49ers expert picks feature our NFL experts with their favorite predictions for Monday Night Football.
Washington Commanders quarterback Jayden Daniels looks to pass the ball as we make our Commanders vs. 49ers expert picks
Pictured: Washington Commanders quarterback Jayden Daniels looks to pass the ball as we make our Commanders vs. 49ers expert picks. Photo by Geoff Burke-Imagn Images
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Week 6 NFL action wraps up tonight with a lopsided-looking affair and our Commanders vs. 49ers expert picks break down all the action and find the best value plays to finish the week on a high note. The 49ers are a 7.5-point favorite ahead of kickoff from Levi's Stadium in 8:15 p.m. ET (ESPN/ABC).

Despite the wide margin on the spread, read on to find out why our experts aren't all aligned with San Francisco recording a blowout victory. 


Commanders vs. 49ers expert picks: Monday Night Football

See all of our experts' NFL picks based on the latest NFL odds.

Expert Pick
Mike Spector Commanders +5.5 first half spread 
LJ Blut Rachaad White to score anytime touchdown
Brenden Schaeffer George Kittle Over 64.5 receiving yards

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Mike Spector's pick: Commanders +5.5 first half spread

San Francisco has the third-largest point differential in the second half this season (plus-31), while Washington has been outscored 95-to-61 after halftime (the league’s second-worst margin). The Commanders defense has also been a sieve in the fourth quarter, allowing an NFL-worst 55 points.

See Mike Spector's full analysis in his Commanders vs. 49ers prediction. 

LJ Blut's pick: Rachaad White to score anytime touchdown

With the Commanders expected to be without starting running back Jacory Croskey-Merritt, White could see an opportunity to make an impact and capitalize on scoring chances.

See LJ Blut's full analysis in his Commanders vs. 49ers touchdown scorer prediction.

Brenden Schaeffer's pick: George Kittle Over 64.5 receiving yards

Kittle has reached 70 or more receiving yards in three of his five games this season and faces a favorable matchup for more damage in this one. Entering Week 6, the Commanders have allowed the fifth-most yards per game to the tight end position.

See Brenden Schaeffer's full analysis in his Commanders vs. 49ers same-game parlay.


How to watch Commanders vs. 49ers: Monday Night Football

  • Date: Monday, Oct. 19
  • Kickoff: 8:15 p.m. ET
  • Location: Levi's Stadium (Santa Clara, Calif.)
  • TV: ESPN/ABC