Colts vs. Vikings Prediction: Week 7 Odds, Picks & Best Bet (Oct. 25)

Our Colts vs. Vikings prediction for Week 7 includes our best bet, projected score, and the latest odds for Sunday's matchup.
Indianapolis Colts quarterback Daniel Jones (17) drops back to pass as he is featured in our Colts vs. Vikings prediction.
Pictured: Indianapolis Colts quarterback Daniel Jones (17) drops back to pass as he is featured in our Colts vs. Vikings prediction. Photo by Grace Hollars/IndyStar / USA TODAY NETWORK via Imagn Images.
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One of the league's last undefeated teams comes off a bye to host an opponent looking to snap a losing slump in my Colts vs. Vikings prediction. 

The Vikings are -6.5-point betting favorites at home from U.S. Bank Stadium in Minneapolis, Minn., leading up to Sunday's kickoff at 1 p.m. ET (CBS). 


Colts vs. Vikings picks & predictions

See all of our experts' NFL picks for Week 7 based on the latest NFL odds.

Pick Odds Bet size
Vikings -6.5 (-105 via FanDuel) 1.05 units to profit 1.00 unit
Under 41.5  (-110 via DraftKings) 2.20 units to profit 2.00 units

Picks submitted: Oct. 24 at 10:45 a.m. ET. Odds subject to change

Total wagered: 3.25 units | Max profit: +3.00 units

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Colts vs. Vikings prediction & best bet

Under 41.5 (-110 via DraftKings)

The real MVP of the 5-0 Vikings has been DC Brian Flores. His aggressive blitz packages and playcalling have led Minnesota to the top of the NFL in points allowed per game (12.8) through 6 weeks. 

Daniel Jones has regressed as the Colts' QB1. Indianapolis' 26-20 loss at home to the Titans in Week 6 led to the firing of long-time GM Chris Ballard. Now, the Colts will try to snap a two-game skid on the road against the league's best scoring defense. 

Jonathan Taylor likely won't fare well against the Vikings. Minnesota has held 3 of 5 opponents under 70 total rushing yards. The Vikings have also forced 2+ turnovers in 4 of 5 matchups. 

The Colts are plagued by turnover woes and miscues, committing 3 against the Titans, including a blocked punt that was returned for a touchdown. 

Minnesota is 4-1 on point total unders this season. The total has steamed down from 44.5 to 41.5. Let's bet this total before it gets any smaller. 

Let's bet Under 41.5 at -110 odds on DraftKings.

📡 SBR Edge: Skoling Under

Dating back to last season, the Vikings have gone Under the point total line in 7 of 8 games played. 

Flores and Vikings Defense Shut Down Colts' Offense

Kyler Murray and the Vikings' offense are beginning to gel and face a porous Colts defense. Expect Minnesota to score at least 21-24 points against a bottom-5 Indianapolis defense. 

This comes down to how the Vikings' top-ranked defense contains Colts RB Jonathan Taylor. He's a high-volume stud, but his production has been trending down. Flores and the Vikings' defense will shut down the Colts for a comfortable win at home to improve to 6-0. 

Play to: Under 38.5

Score prediction: Vikings 24, Colts 13


Live Colts vs. Vikings odds

See the latest odds movement and more on our Colts vs. Vikings matchup page.

Colts vs. Vikings opening odds

  • Moneyline: Colts +200 | Vikings -250
  • Spread: Colts +5.5 (-110) | Vikings -5.5 (-110)
  • Over/Under: Over 44.5 (-105) | Under 44.5 (-115)

Colts vs. Vikings weather

Weather will be a non-factor with this game being played in a dome at U.S. Bank Stadium. 


Latest Colts vs. Vikings injuries


How to watch Colts vs. Vikings: Week 7

  • Date: Sunday, Oct. 25
  • Kickoff: 1:00 p.m. ET
  • Location: U.S. Bank Stadium (Minneapolis, Minn.)
  • TV/Streaming: CBS