Cardinals vs. Panthers Picks, Predictions NFL Week 4: Can Carolina Keep Dominating Arizona?
The Carolina Panthers visit the Arizona Cardinals in Week 4 with both teams sitting at 1-2 straight up and against the spread. Check out our top Panthers-Cardinals picks below.
Arizona has suffered losses against the Kansas City Chiefs and rival Los Angeles Rams, while coming from behind for a 29-23 overtime win against the Las Vegas Raiders in Week 2. The only game the Cardinals won was the one in which they closed as the underdogs.
The Panthers entered the win column for the first time in 2022 with a 22-14 win over the New Orleans Saints last week. They had previously lost to the Cleveland Browns and New York Giants.
Check out all of our top NFL Week 4 picks here.
Here are our top Cardinals-Panthers NFL Week 4 picks (odds via Caesars Sportsbook, FanDuel Sportsbook and DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).
Cardinals vs. Panthers Game Info
- Date: Sunday, Oct. 2, 4:05 p.m. ET
- TV: FOX
- Location: Bank of America Stadium, Charlotte, NC
- Weather: 66 degrees, 25% chance of precipitation, 8-mph winds
Cardinals vs. Panthers Odds
Cardinals vs. Panthers Odds Analysis
This game is now a pick'em after opening at a consensus line of Cardinals -2.5. Eighty-two percent of the tickets and 85% of the handle are backing Arizona.
The Over/Under has dropped from an opener of 46.5 to 43.5. The Under has drawn 52% of the handle on just 26% of the tickets.
Cardinals vs. Panthers Picks
- Cardinals ML (+105 via Caesars) ★★★★★
- Under 43.5 (-110 via FanDuel) ★★★★
- Brown Over 57.5 receiving yards (-115 via DraftKings) ★★★★★
Cardinals vs. Panthers ATS Pick
Cardinals ML (+105) ★★★★★
It’s strange for Arizona to be the underdog, despite recent history between these two teams. In fact, some sportsbooks can’t decide one way or another. For example, DraftKings currently has both opponents as -110 on the moneyline, which you don’t often see.
The Cardinals are the better team with higher expectations, making this contest a lot more important to them. Quarterback Kyler Murray and Co. know they can't lose many more games if they hope to be a serious contender. They’ll get some help this week when wide receiver Rondale Moore is expected to return. Panthers star running back Christian McCaffrey may also be absent, which spells an even tougher situation for Carolina.
Cardinals vs. Panthers O/U Pick
Under 43.5 (-110) ★★★★
This total has slipped three full points since opening, showing that oddsmakers don’t mess around when it comes to adjusting lines. The fall could be for several reasons, including McCaffrey’s lack of practice participation.
Both teams have scored exactly 62 points through three games, meaning the result of this market could be a photo finish. The Under does seem more probable, however, even if only slightly.
Cardinals vs. Panthers Prop Pick
Brown Over 57.5 receiving yards (-115) ★★★★★
Arizona wideout Marquise ‘Hollywood’ Brown has been fed like a spoiled child in terms of targets this season. Brown has 24 receptions on 34 targets with an average of over 10 yards per reception, through three games. His usage has continually ramped up since Week 1, thanks to Moore and Hopkins' absences.
Even with Moore set to return, Brown has quickly become Murray’s favorite toy. It’s tough to imagine a scenario where Hollywood doesn’t smash this prop.
Where to Bet on Cardinals vs. Panthers Picks
Here are our top-rated sportsbooks:
SEE ALSO: All picks, odds, and sports betting news. Be sure to check out SportsbookReview.com’s community forums and betting tools.
Cardinals-Panthers picks made 9/30/2022 at 3:29 p.m. ET
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