Utah vs. Iowa State Prediction: Week 4 Odds, Picks & Best Bet
No. 15 Utah looks to keep its unbeaten season alive in a road contest against Iowa State, and my Utah vs. Iowa State prediction expects a higher-scoring game as each team’s new head coaches have instilled more offensive firepower than the old regimes.
Kickoff from Jack Trice Stadium in Ames is scheduled for 3:30 p.m. ET on Saturday afternoon, airing on FOX. Utah is an 8.5-point betting favorite.
🏈 Utah vs. Iowa State picks & predictions
See all of our experts' college football picks for Week 4 based on the latest college football odds.
| Pick | Bet size |
|---|---|
| ATS: Utah -8 (-110 via BetMGM) | 0.5 units to win 0.46 units |
| O/U: Over 48.5 (-105 via DraftKings) | 1 unit to win 0.95 units |
Total wagered: 1.5 units | Max profit: 1.41 units
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💰 Utah vs. Iowa State prediction & best bet
Check out all of our college football predictions for more analysis across this week's slate.
Over 48.5 (-105 via DraftKings)
Utah’s Devon Dampier is one of the best quarterbacks in the country that many have likely never heard of. He is running new offensive coordinator Kevin McGiven’s system brilliantly after finishing seventh in Total QBR last season.
New Utes head coach Morgan Scalley has been on the staff since 2006, and served as the defensive coordinator from 2016-25. While his defenses ranked in the top 25 in points per game allowed in each of the last three seasons, it’s the offense that has made headlines so far. Right from the start, Utah’s 66 points in its season opener against Idaho was its most to open a season in more than a century.
Iowa State played its annual rockfight against Iowa this year (a 16-13 loss), but the Cyclones are coming off their most rushing yards in a game (365) since 2011.
📡 SBR Edge- Overs as favorites
The Over has cashed in 62.5% of Utah's games as a favorite since the start of the 2025 season (10 of 16).
McGiven is an offensive guru
McGiven spent last season as Utah State’s offensive coordinator, where the Aggies ranked second in the Mountain West in points per game and yards per play. Thus far, Devon Dampier looks comfortable in that new system, logging a 7-to-1 touchdown-to-interception ratio and ranking in the top 20 in QBR.
McGiven looks to help add to Utah’s streak of scoring 30-plus points in nine straight games, which is the longest active streak among FBS teams. The Utes have also put up 440-plus yards in all three games, and I’m selling high on their defense that has kept back-to-back opponents under 100 rushing yards.
Score prediction: Utah 31, Iowa State 20
📊 Live Utah vs. Iowa State odds
See the latest college football odds for every Week 4 matchup.
Utah vs. Iowa State opening odds
- Moneyline: Utah -450 | Iowa State +350
- Spread: Utah -10.5 (-105) | Iowa State +10.5 (-112)
- Over/Under: Over 49.5 (-108) | Under 49.5 (-112)
📺 How to watch Utah vs. Iowa State: Week 4
- Date: Saturday, Sept. 26
- Kickoff: 3:30 p.m. ET
- Location: Jack Trice Stadium (Ames, Iowa)
- TV: FOX
- Streaming: YouTube TV
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Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
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