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USC vs. Oregon State Picks, Predictions Week 4 College Football: Surging Trojans' Offense Take Act on the Road

Brenden Schaeffer

Last Updated: January 1, 0001 12:00 AM EST • 1 min 32 sec read.

Quarterback Caleb Williams of the USC Trojans sets to pass against the Fresno State Bulldogs at United Airlines Field on Sept. 17, 2022 in Los Angeles, California
Quarterback Caleb Williams of the USC Trojans sets to pass against the Fresno State Bulldogs at United Airlines Field on Sept. 17, 2022 in Los Angeles, California. Photo by Jayne Kamin-Oncea/Getty Images via AFP.

One of the highest FBS totals this weekend makes for some glorious after dark PAC-12 action, as the USC Trojans take on the Oregon State Beavers. Read on for our USC-Oregon State picks.

USC looks to be back with head coach Lincoln Riley’s offense one of the top units in the country. Will the Trojans race past Oregon State in Corvallis? 

Here are our top picks for USC-Oregon State (odds via FanDuel Sportsbook and DraftKings Sportsbook). 

USC vs. Oregon State Picks

  • USC -5.5 (-110 odds via FanDuel) ★★★★
  • Over 70.5 (-110 odds via FanDuel and DraftKings) ★★★
  • Williams Over 294.5 Passing Yards (-115 odds via DraftKings) ★★★

USC vs. Oregon State ATS Pick

USC -5.5 (-110) ★★★★

USC’s offense has been elite this season, with the Trojans' 50.7 points per game ranking FBS 4th. They’ve even done this without facing an FCS opponent in three games.

Oregon State is 3-0 against the spread this season, but so is USC. I’m riding with their 31-point average margin of victory in a game they only need to win by a touchdown to cover. Bet it at FanDuel (-5.5) over DraftKings (-6) for the extra edge on the odds.

USC vs. Oregon State O/U Pick

Over 70.5 (-110) ★★★

This is one of the highest FBs totals this weekend--and with these two offenses, it’s non far-fetched to think it’s going to hit. Oregon State and USC have both seen the Over go 2-1 in their games so far this year.

The Beavers are no slouch, averaging 34.5 PPG to rank inside the top 40. Defensively, their opponents’ PPG against FBS teams is 24.5, which ranks outside the top 50. Oregon State also allowed 28 points, though, to FCS Montana State. I don’t see their defense keeping the Trojans below the mid-40s.

USC vs. Oregon State Prop Pick

Williams Over 294.5 passing yards (-115) ★★★

USC quarterback Caleb Williams threw for 341 yards and four touchdowns in his only conference game this season, a win over Stanford. The Trojans' passing attack has been the driving force behind their success this season and the Oklahoma transfer looks up to the task.

Oregon State gives its opponents an average of 272.5 passing yards per game, ranking 98th in FBS. That spells a passing defense that USC can exploit with aplomb.

Where to Bet on USC vs. Oregon State Picks

Here are our top-rated sportsbooks:

SEE ALSO: All picks, odds, and sports betting news. Be sure to check out SportsbookReview.com’s community forums and betting tools.

USC-Oregon State picks made 9/23/2022 at 6:44 p.m. ET

Written By:
Brenden Schaeffer
Since graduating from the University of Missouri in 2016, Brenden Schaeffer has covered the St. Louis Cardinals and Blues hockey as a writer for KMOV in St. Louis. He also co-hosts 'The Big Show' on KTGR radio in Columbia, Missouri. The show airs in afternoon drive, weekdays from 4-6 p.m. Brenden has contributed to SBR since 2021, providing insights on NFL, NCAAF, NCAAB, and the NBA. You can download his daily baseball podcast, B-Schaeff Daily, on Spotify or Apple podcasts, and you can find Brenden across social media @bschaeffer12.