Oklahoma State vs. West Virginia Prediction: Week 4 Odds, Picks & Best Bet
My best Oklahoma State vs. West Virginia prediction focuses on Drew Mestemaker and the Oklahoma State passing attack taking care of business against West Virginia's struggling secondary. West Virginia is coming off a huge win over Virginia, which is a big reason why this line has shifted from Oklahoma State favored by 2.5 to West Virginia favored by 1.5.
Saturday's action starts at 7 p.m. ET and will be played at Milan Puskar Stadium in Morgantown, W.Va. The game will air on FS1 and stream on FOX One.
🏈 Oklahoma State vs. West Virginia picks & predictions
See all of our experts' college football picks for Week 4 based on the latest college football odds.
| Pick | Bet size |
|---|---|
| ML: Oklahoma State (+105 via DraftKings) | 2 units to win 2.1 units |
| O/U: Under 61.5 (-112 via BetMGM) | 1 unit to win 0.89 units |
Total wagered: 3 units | Max profit: 2.99 units
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💰 Oklahoma State vs. West Virginia prediction & best bet
Check out all of our college football predictions for more analysis across this week's slate.
Oklahoma State ML (+105 via DraftKings)
After an abysmal Week 1 that resulted in a 24-10 loss to Tulsa, Oklahoma State has rebounded incredibly, knocking off Oregon and dominating FCS Murray State. Led by Mestemaker, Oklahoma State has the 18th-best passing attack in the country, and that's going to be the difference in this game.
West Virginia's pass defense is among the worst in the nation, ranking 114th and allowing 246.7 yards per game.
What makes Oklahoma State's offense even more dangerous for the nation's 93rd-ranked defense is that it's far from one-dimensional. Led by Caleb Hawkins, Oklahoma State ranks 29th in rushing yards per game and 33rd in rushing yards per carry.
📡 SBR Edge
Mestemaker completed 90.9% of his passes last week, and while he won't hit that number this week, West Virginia's defense ranks 84th in opponent completion percentage.
Oklahoma State's defense slams the door
Oklahoma State ranks 26th in total defense, allowing just 267.3 yards per game. And don't assume this is just because of playing Tulsa and Murray State. Oklahoma State held Oregon to just 281 total yards and 12 first downs two weeks ago.
West Virginia relies heavily on the run, averaging 281.3 rushing yards per game, which ranks sixth-best in the nation. But West Virginia ranks 40th in yards per carry, which is why I think the nation's 35th-ranked rush defense actually has the advantage in this game.
Score prediction: Oklahoma State 31 West Virginia 27
📊 Oklahoma State vs. West Virginia odds
See the latest college football odds for every Week 4 matchup.
Oklahoma State vs. West Virginia opening odds
- Moneyline: Oklahoma State -150 | West Virginia +125
- Spread: Oklahoma State -2.5 (-110) | West Virginia +2.5 (-110)
- Over/Under: Over 57.5 (-110) | Under 57.5 (-110)
📺 How to watch Oklahoma State vs. West Virginia: Week 4
- Date: Saturday, Sept. 26
- Kickoff: 7 p.m. ET
- Location: Milan Puskar Stadium (Morgantown, W.V.)
- TV: FS1
- Streaming: FOX One
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Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
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