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LSU vs. Auburn Picks, Predictions College Football Week 5: Bayou Bengals Hold Edge

Brenden Schaeffer

Last Updated: September 30, 2022 3:51 PM EDT • 1 min 24 sec read.

Running back Tank Bigsby of the Auburn Tigers runs the ball by defensive lineman Isaiah Iton of the Mississippi Rebels at Jordan-Hare Stadium on Oct. 30, 2021 in Auburn, Alabama.
Running back Tank Bigsby of the Auburn Tigers runs the ball by defensive lineman Isaiah Iton of the Mississippi Rebels at Jordan-Hare Stadium on Oct. 30, 2021 in Auburn, Alabama. Photo by Michael Chang/Getty Images via AFP.

Can head coach Bryan Harsin survive another week by having his Auburn Tigers ready for rival head coach Brian Kelly’s LSU Tigers? Read on for best our LSU-Auburn picks.

Harsin arguably has the hottest coaching seat in Power Five. Kelly’s LSU team can snare its first road win and open up a head job at an SEC West rival in one fell swoop this weekend.

Here are our top LSU-Auburn picks (odds via DraftKings Sportsbook and FanDuel Sportsbook).

LSU vs. Auburn Picks

  • LSU -8 (-110 odds via DraftKings) ★★★★
  • Under 45.5 (-110 odds via FanDuel and DraftKings) ★★★
  • Ashford Under 149.5 passing yards (-114 odds via FanDuel) ★★★

LSU vs. Auburn ATS Pick

LSU -8 (-110) ★★★★

LSU hasn’t played a road game yet under Kelly, a variable we won’t be able to quantify. But we know the Bayou Bengals boast college football's 10th-best defense and 20th-best offense according to ESPN’s Football Power Index. 

Per the metrics, Auburn isn’t close, ranking 91st in offensive efficiency and 84th in defensive efficiency, per FPI. To the eye-test, they were remarkably fortunate not to lose to Missouri at home last week.

LSU vs. Auburn O/U Pick

Under 45.5 (-110) ★★★

LSU should take command of this game with its distinct advantage both offensively and defensively. The question is whether Auburn can help LSU carry the burden.

The Bayou Bengals average 30.7 points per game this season. Auburn needed overtime to get to 17 last week against a lesser defense. If LSU has any first-road game jitters, it's unlikely it'll score enough to carry an out-matched Auburn offense Over this total.

LSU vs. Auburn Prop Pick

Ashford Under 149.5 passing yards (-114) ★★★

Auburn quarterback Robby Ashford can move the ball effectively in conjunction with running back Tank Bigsby for the Auburn rushing attack. Ashford has been severely limited through the air, though. 

LSU ranks 15th defensively in FBS, allowing just 173.7 passing yards per game. Ashford mustered 127 passing yards last week against Missouri. Though Ashford is the last man standing in the Auburn QB room, he’s not an effective volume passer.

Where to Bet on LSU vs. Auburn Picks

Here are our top-rated sportsbooks:

SEE ALSO: All picks, odds, and sports betting news. Be sure to check out SportsbookReview.com’s community forums and betting tools.

LSU-Auburn picks made 9/30/2022 at 3:51 p.m. ET

Written By:
Brenden Schaeffer
Since graduating from the University of Missouri in 2016, Brenden Schaeffer has covered the St. Louis Cardinals and Blues hockey as a writer for KMOV in St. Louis. He also co-hosts 'The Big Show' on KTGR radio in Columbia, Missouri. The show airs in afternoon drive, weekdays from 4-6 p.m. Brenden has contributed to SBR since 2021, providing insights on NFL, NCAAF, NCAAB, and the NBA. You can download his daily baseball podcast, B-Schaeff Daily, on Spotify or Apple podcasts, and you can find Brenden across social media @bschaeffer12.