Liberty vs. Coastal Carolina Prediction: Week 4 Odds, Picks & Best Bet

Our Liberty vs. Coastal Carolina prediction for Week 4 includes our best bet, projected score, and the latest odds for Thursday's matchup.
Coastal Carolina Chanticleers quarterback Deuce Bailey (2) throws a pass as he is featured in our Liberty vs. Coastal Carolina prediction.
Pictured: Coastal Carolina Chanticleers quarterback Deuce Bailey (2) throws a pass as he is featured in our Liberty vs. Coastal Carolina prediction. Photo by Ben Queen-Imagn Images
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We've got a standalone G6 matchup on Thursday night for my Liberty vs. Coastal Carolina prediction. It's Conference USA against the Sun Belt, and the Flames enter with momentum after a 51-point offensive explosion, while the Chanticleers fell to 1-2 with a road loss to Delaware. 

Liberty is currently a -2.5-point road favorite at Brooks Stadium in Conway, S.C., ahead of Thursday night's opening kickoff set for 7:30 p.m. ET (ESPN). 


🏈 Liberty vs. Coastal Carolina picks & predictions

See all of our experts' college football picks for Week 4 based on the latest college football odds.

Pick Bet size
Liberty -2.5 (-110 via BetMGM) 1.10 units to win 1.0 units
Under 50.5 (-110 via BetMGM) 1.10 units to win 1.0 units

Total wagered: 2.20 units | Max profit: 2.0 units

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💰 Liberty vs. Coastal Carolina prediction & best bet

Check out all of our college football predictions for more analysis across this week's slate.

Under 50.5 (-110 via BetMGM)

I flip flopped a bit on my best bet for this game. Liberty appears to be the side to back on paper, especially after a 51-14 win over Ball State in Week 3. Ultimately, I've settled for Under 50.5, as Coastal Carolina hosts its first FBS opponent in 2026. 

The public is hammering Over 50.5 points in this matchup. 89 percent of public bettors are taking Over 50.5, creating value on the point total under. 

Liberty is the key to this under hitting. The Flames have not allowed more than 23 points to an opponent in 2026, and ironically, Gardner-Webb (FCS) managed to outscore James Madison and Ball State. 

Liberty has allowed a stingy 49.4 percent completion rate, while forcing 4 turnovers in its last two contests. Coastal Carolina's offense relies heavily on its passing attack, so expect the Chanticleers to get bottled up by the Flames' secondary. 

The point total has already dropped from 54.5 to 50.5. We missed the high-value opportunity, but Liberty's pass defense, plus the public side of Over 50.5, means Under 50.5 is the best bet in this Thursday night matchup. 

📡 SBR Edge: Flamin' Unders

Seven of Liberty's previous eight non-conference games have gone under the point total line. 

Liberty's pass defense limits Coastal Carolina's offense

Coastal Carolina QB Deuce Bailey's impressive arm talent gets reigned in against Liberty in this game. Despite having over 800 passing yards for 8 touchdowns and zero interceptions, Bailey only has a 55.7 percent completion rate.

The Chanticleers' offense leans on its passing attack, failing to score a rushing touchdown against either of its FBS opponents this season. Coastal Carolina has also lost 2 fumbles in each of its losses to West Virginia and Delaware. The Flames' secondary will hold Bailey out of the end zone and force a couple of turnovers to win this game on the road. 

Score prediction: Liberty 27, Coastal Carolina 23


📊 Liberty vs. Coastal Carolina odds

See the latest college football odds for every Week 4 matchup.

Liberty vs. Coastal Carolina opening odds

  • Moneyline: Liberty -102 | Coastal Carolina -118
  • Spread: Liberty +1.5 (-108) | Coastal Carolina -1.5 (-112)
  • Over/Under: Over 54.5 (+100) | Under 54.5 (-120)

📺 How to watch Liberty vs. Coastal Carolina: Week 4

  • Date: Thursday, Sept. 24
  • Kickoff: 7:30 p.m. ET
  • Location: Brooks Stadium (Conway, S.C.)
  • TV: ESPN

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Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)