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The Kansas Jayhawks offense runs the ball against the Duke Blue Devils defense during the first half at David Booth Kansas Memorial Stadium on Sept. 24.
The Kansas Jayhawks offense runs the ball against the Duke Blue Devils defense during the first half at David Booth Kansas Memorial Stadium on Sept. 24. Photo by Jay Biggerstaff / Getty Images via AFP

The Kansas Jayhawks are looking to shed the label of being “just a basketball school” as they have started the season 4-0. Read on for our best ATS bets for Week 5’s college football action.

Three AP top 25 teams lost to unranked opponents last week, so there is sure to be some reshuffling in the polls this week.

Below, we offer our top ATS bets for Week 5 in college football (odds via FanDuel Sportsbook, DraftKings Sportsbook, and BetMGM; pick confidence based on a 1-to-5-star scale).

Top ATS Bets of Week 5

Top ATS Predictions of Week 5

Minnesota -9.5 (-110) ★★★★

This line is subject to a lot of change given the uncertainty surrounding Purdue quarterback Aidan O’Connell’s playing status. O’Connell was considered a game-time decision but was eventually ruled out last week against FAU, which led to Austin Burton’s first start for Purdue. Burton started well, going 6-for-6 on the first drive, but looked like the inexperienced quarterback he is on the following four possessions, which resulted in zero points and included a lost fumble.

Minnesota’s Mohamed Ibrahim entered last week tied for first in the country with seven rushing touchdowns and 24 missed tackles, and his 31 rushes of 10+ yards were second-most in FBS. Ibrahim added 103 yards and a touchdown against Michigan State last week and will be a handful for Purdue’s rush defense that ranks eighth in the Big Ten, allowing 115.8 yards per game.

This line will assuredly move to double-digits if O’Connell is again ruled out, so grab this number at FanDuel while you can, as it provides way better value than the other sportsbooks offering -10 or -10.5.

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

Oklahoma -4.5 (-110) ★★★★★

Many will write off Oklahoma after Saturday’s disappointing 41-34 home loss to Kansas State. However, casual bettors should understand that the loss was not as big of an upset as it has been made out to be, as the Sooners are 1-3 versus Kansas State since 2019, with multiple losses to the Wildcats as 21-point favorites. Thus, Oklahoma has had its share of struggles with Kansas State but is still 22-3 against all other Big 12 opponents in the last three seasons.

Conversely, TCU has won just four conference games over the last three seasons outside of games against Texas Tech and Kansas. The Horned Frogs rank seventh in the Big 12 in total defense (373 yards per game allowed) and will be challenged by Oklahoma’s explosive offense led by Dillon Gabriel, who entered the season ranked third among all FBS quarterbacks in touchdown passes.

TCU has not beaten Oklahoma as a member of the Big 12 since 2014 and Oklahoma’s last six wins in the rivalry have come by an average of 18.5 points per game. Look for the Sooners to get right in this road contest.

Kansas +3.5 (-110) ★★★

Is it too soon to give Kansas head coach Lance Leipold the Coach of the Year award? Kansas had the fifth-longest stretch of all Power Five teams without starting a season 4-0 but snapped that streak that dated back to 2009 with Saturday’s 35-27 win over then-unbeaten Duke. Kansas’ 159 points through its first three games were the program’s most since 2007, and Jalon Daniels’ 98 total QBR entering Week 4 led all FBS quarterbacks.

Leipold is the fastest coach in NCAA history to reach 100 career wins. Two of his captains are transfers who followed him from Buffalo, which helped ease a 45% roster turnover rate since 2021. 

Last week, Kansas was favored against a Power 5 school for the first time in 13 years. However, the team hasn’t been too shabby as underdogs either, going 2-0 this year following a stretch of three wins in 29 games as underdogs over the last three seasons. We look for the Jayhawks to continue their success as home ‘dogs this week.

Where to Bet on College Football ATS Picks

Here are our top-rated sportsbooks:

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook

SEE ALSO: All picksodds, and sports betting news. Be sure to check out’s community forums and betting tools.

College football top ATS bets from 9/26/2022 at 7:14 a.m. ET.