Panthers vs. Hurricanes Prediction & Odds: NHL Picks (Sept. 29)
Last Updated: September 28, 2026 8:00 AM EDT • 2 minute read X Social Google News Link
Winners of the previous three Stanley Cups meet at Lenovo Center in Raleigh, N.C., as the puck drops on the 2026-27 NHL season (5 p.m. ET, ESPN), and I’m featuring my Panthers vs. Hurricanes prediction for the mouthwatering proposition.
The Hurricanes are the -128 betting favorite for Tuesday's game, and I’m backing Rod Brind’Amour’s team to start their championship defense with a win. I’m also expecting goals galore, as has become customary recently between these Eastern Conference foes.
Panthers vs. Hurricanes picks & odds: Sept. 29
See all of our experts' NHL picks based on the latest NHL odds.
| Pick | Odds | Bet size |
|---|---|---|
| Hurricanes ML | -128 via FanDuel | 1 unit |
| Over 6.5 goals | +100 via FanDuel | 1 unit |
📃 Affiliate disclosure
Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
Panthers vs. Hurricanes prediction & best bet
Hurricanes ML (-128 via FanDuel)
The reigning Stanley Cup champions meet a team one year removed from back-to-back Cups, and it should be a doozy. I’m leaning on the Hurricanes to continue a trend of Stanley Cup winners kicking off the subsequent campaign successfully.
Defending champs won the previous four banner-raisers and have a 7-1-2 record in the last 10. Overall, the champs boast an outrageously good 63-26-16 record.
The Panthers will no doubt be back to their best this season, but the Hurricanes will enjoy a surge of adrenaline from seeing the banner lifted to the rafters.
Score prediction: Hurricanes 4, Panthers 3
Best Panthers vs. Hurricanes Over/Under bet: Over 6.5 goals
I also expect offensive fireworks, with their last four meetings averaging eight goals per game. Excluding Brad Marchand, who will be out until November at the earliest, the Panthers have a relatively clean bill of health.
Brady Tkachuk is expected to make his Panthers’ regular-season debut despite suffering an undisclosed injury in the preseason opener against the Hurricanes.
The Panthers beat the Hurricanes 6-3 in that game. While I don’t think we’ll get nine goals, I’m confident we’ll see the trend of goals galore continue.
📊 Live Panthers vs. Hurricanes odds
🚑 Panthers vs. Hurricanes injuries
📺 How to watch Panthers vs. Hurricanes
- Date: Tuesday, Sept. 29
- Puck drop: 5 p.m. ET
- Location: Lenovo Center (Raleigh, N.C.)
- TV: ESPN
- Streaming: ESPN+
Gary Pearson X social