Panthers vs. Hurricanes Prediction & Odds: NHL Picks (Sept. 29)

The puck drops on the 2026-27 NHL season as I offer my Panthers vs. Hurricanes prediction and odds.
Pictured: Seth Jarvis and Eric Robinson in action as we break down our Panthers vs. Hurricanes Prediction & Odds. Photo by James Guillory-Imagn Images.
Pictured: Seth Jarvis and Eric Robinson in action as we break down our Panthers vs. Hurricanes Prediction & Odds. Photo by James Guillory-Imagn Images.
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Winners of the previous three Stanley Cups meet at Lenovo Center in Raleigh, N.C., as the puck drops on the 2026-27 NHL season (5 p.m. ET, ESPN), and I’m featuring my Panthers vs. Hurricanes prediction for the mouthwatering proposition. 

The Hurricanes are the -128 betting favorite for Tuesday's game, and I’m backing Rod Brind’Amour’s team to start their championship defense with a win. I’m also expecting goals galore, as has become customary recently between these Eastern Conference foes. 


Panthers vs. Hurricanes picks & odds: Sept. 29

See all of our experts' NHL picks based on the latest NHL odds.

Pick Odds Bet size
Hurricanes ML  -128 via FanDuel 1 unit
Over 6.5 goals  +100 via FanDuel  1 unit

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Panthers vs. Hurricanes prediction & best bet

Hurricanes ML (-128 via FanDuel)

The reigning Stanley Cup champions meet a team one year removed from back-to-back Cups, and it should be a doozy. I’m leaning on the Hurricanes to continue a trend of Stanley Cup winners kicking off the subsequent campaign successfully. 

Defending champs won the previous four banner-raisers and have a 7-1-2 record in the last 10. Overall, the champs boast an outrageously good 63-26-16 record. 

The Panthers will no doubt be back to their best this season, but the Hurricanes will enjoy a surge of adrenaline from seeing the banner lifted to the rafters. 

Score prediction: Hurricanes 4, Panthers 3


Best Panthers vs. Hurricanes Over/Under bet: Over 6.5 goals

I also expect offensive fireworks, with their last four meetings averaging eight goals per game. Excluding Brad Marchand, who will be out until November at the earliest, the Panthers have a relatively clean bill of health. 

Brady Tkachuk is expected to make his Panthers’ regular-season debut despite suffering an undisclosed injury in the preseason opener against the Hurricanes. 

The Panthers beat the Hurricanes 6-3 in that game. While I don’t think we’ll get nine goals, I’m confident we’ll see the trend of goals galore continue. 


📊 Live Panthers vs. Hurricanes odds


🚑 Panthers vs. Hurricanes injuries


📺 How to watch Panthers vs. Hurricanes

  • Date: Tuesday, Sept. 29
  • Puck drop: 5 p.m. ET
  • Location: Lenovo Center (Raleigh, N.C.)
  • TV: ESPN
  • Streaming: ESPN+