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NFL Week 18 Picks Roundup

Sportsbook Review

Last Updated: January 9, 2022 7:29 AM EST • 63 sec read.

INDIANAPOLIS, INDIANA - JANUARY 02: Derek Carr #4 of the Las Vegas Raiders throws a pass during the second half against the Indianapolis Colts at Lucas Oil Stadium on January 02, 2022 in Indianapolis, Indiana. Justin Casterline/Getty Images/AFP (Photo by Justin Casterline / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

Check out all of our NFL picks and predictions for Week 18.

The first-ever Week 18 of an NFL season starts with two games on Saturday and has another 14 on Sunday. Six division titles are wrapped up but only the Green Bay Packers have fully secured their playoff position by clinching the No. 1 seed in the NFC last week.

Here are our against the spread and Over/Under NFL Week 18 picks (click each link for a full preview).

NFL Week 18 Picks

Sunday, 4:25 p.m. ET

New York Jets vs. Buffalo Bills | Jets +16.5 | Over 41Jets: SU: 4-12 | ATS: 6-10 | O/U: 10-6Bills: SU: 10-6 | ATS: 8-6-2 | O/U: 8-8

Carolina Panthers vs. Tampa Bay Buccaneers | Buccaneers -8 | Under 41.5Panthers: SU: 5-11 | ATS: 5-11 | O/U: 7-9Buccaneers: SU: 12-4 | ATS: 8-8 | O/U: 8-8

San Francisco 49ers vs. Los Angeles Rams | 49ers +4.5 | Over 44.549ers: SU: 9-7 | ATS: 8-8 | O/U: 7-9Rams: SU: 12-4 | ATS: 8-8 | O/U: 8-7-1

SEE ALSO:Top NFL Prop Picks for Week 18

New England Patriots vs. Miami Dolphins | Dolphins +6.5 | Under 40Patriots: SU: 10-6 | ATS: 10-6 | O/U: 8-8Dolphins: SU: 8-8 | ATS: 8-7-1 | O/U: 6-10

Seattle Seahawks vs. Arizona Cardinals | Seahawks +5.5 | Under 48.5Seahawks: SU: 6-10 | ATS: 8-8 | O/U: 5-11Cardinals: SU: 11-5 | ATS: 10-6 | O/U: 7-9

Sunday Night Football

Los Angeles Chargers vs. Las Vegas Raiders | Chargers -3 | Over 49.5Chargers: SU: 9-7 | ATS: 8-8 | O/U: 9-7Raiders: SU: 9-7 | ATS: 7-9 | O/U: 7-9

SEE ALO: Chargers vs. Raiders Prop Picks

SEE ALSO: All picks and odds. Be sure to check out SportsbookReview.com’s community forums and betting tools.

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