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James Harden of the Philadelphia 76ers passes the ball against the Dallas Mavericks at American Airlines Center on Mar. 2, 2023 in Dallas, Texas.
James Harden of the Philadelphia 76ers passes the ball against the Dallas Mavericks at American Airlines Center on Mar. 2, 2023 in Dallas, Texas. Photo by Ron Jenkins/Getty Images via AFP.

The Milwaukee Bucks owned the East to this point, but the Philadelphia 76ers could surprise on Saturday after faring impressively against a tough recent schedule. Read on for our top 76ers vs. Bucks NBA picks based on the best NBA odds.

The Bucks (45-17) are one of the league's pre-eminent home performers this season but the 76ers (40-22) should enter Saturday’s primetime Eastern Conference clash with plenty of motivation to score a defining road win.

After the recent scheduling gauntlet Philly faced, will the Sixers have enough in the tank to keep things competitive in Milwaukee?

Here is our best 76ers vs. Bucks NBA pick (odds via DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).

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76ers vs. Bucks pick

76ers +4.5 (-105 via DraftKings) ⭐⭐⭐⭐

The Bucks dominated opponents who dared to challenge them inside the Fiserv Forum this year, going 27-5 outright and 20-11-1 ATS in their home venue. Although the 76ers haven’t been impressive in road matchups this season (14-14 ATS), I’ve seen enough grit from Philly to expect a battle in Milwaukee.

The Sixers faced winning teams--including games against the NBA’s top contenders--in 10 of their last 11 contests, going 6-5 while avoiding losing by a margin greater than 7 points since February 5.

Philly averaged 122.5 points per game on this current road trip and should have the offensive horsepower to keep up if this matchup takes on a higher-scoring tenor than previous meetings in Philadelphia.

The Sixers fell 90-88 to the Bucks in October before getting the better of them in November, 110-102. Milwaukee won an incredible 16 consecutive games heading into Saturday, so it's not an outright triumph for the visitors. But look for Philadelphia to play like this game has meaning, keeping things respectable in what could be an Eastern Conference Finals preview.

76ers vs. Bucks best odds

DraftKings: 76ers +4.5 (-105) ⭐⭐⭐⭐

DraftKingsFanDuelBetMGMCaesarsPointsBet
76ers +4.576ers +4.576ers +4.576ers +4.576ers +4.5
-105-106-110-110-110

Following the initial push from 76ers +5.5 down to +4.5, DraftKings and FanDuel are two spots to keep an eye on for a potential move back toward the original line. 

While the entire board has Philly at +4.5, those two books list the Sixers at -105 and -106 odds, respectively. That’s an improvement over the -110 odds at the rest of our recommended books. If the line gets back to the original +5.5, this play becomes a five-star pick.

76ers vs. Bucks odds

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76ers vs. Bucks odds analysis

Milwaukee opened as a 5.5-point home favorite but saw that number move to -4.5 across the board. Still, the Bucks dominated in terms of action, seeing 64% of point-spread wagers.

The total opened at 228.5 and saw sharp movement to between 231 and 231.5 across our affiliated sportsbooks. 62% of bets on the total came on the Over.

76ers vs. Bucks game info

  • Date: Saturday, Mar. 4, 2023, 8:30 p.m. ET
  • TV: ABC
  • Location: Fiserv Forum, Milwaukee, WI

76ers-Bucks pick made 3/4/2023 at 11:38 a.m. ET.

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