⚾ MLB Best Home Run Predictions Today: Best HR Props, Picks, Parlay & Odds For Sunday, Sept. 27
The 2026 MLB regular season comes to its conclusion on Sunday, so we've got one more chance to bet a full 15-game slate with my home run predictions today. Saturday's 0-3 outing settled as a third straight losing day.
My MLB home run picks for today's slate include star hitters like Elly De La Cruz. The Reds' shortstop faces Max Scherzer today, who is allowing a ton of contact at the plate, while giving up 11 earned runs in his previous 3 starts for the Blue Jays.
βΎ Home run predictions today: MLB HR picks & odds Sept. 27
See all of our expertsβ MLB picks based on the latest MLB odds.
| π£ Home run pick | π΅ Units | π Notes |
|---|---|---|
| Elly De La Cruz (+410 via FanDuel) | 0.25u β 1.02u | De La Cruz has hit 2 home runs in his last 5 contests. |
| Christian Walker (+400 via bet365) | 0.25u β 1.00u | Walker has logged 3 home runs in his previous 5 outings. |
| Munetaka Murakami (+375 via DraftKings) | 0.27u β 1.01u | Kyle Freeland has allowed 6 home runs in his previous 4 starts. |
Total wagered: 0.77 units | Max profit: 3.03 units
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π£ Best home run predictions & odds today
Home run pick: Elly De La Cruz (+410)
De La Cruz tops the charts in power-hitting metrics this year. He's in the 100th percentile in avg exit velo (94.7 mph) and the 96th percentile or better in xSLG (.507), hard-hit percentage (53.5), and barrel percentage (16.4).
The switch-hitter has also recorded 2 home runs in his previous 5 appearances for the Reds. In September, De La Cruz has 9 home runs.
Scherzer's allowed a home run in 3 of his past 4 starts for the Blue Jays. He's also ranked 25th in hard-hit percentage allowed (8.8).
Bet De La Cruz's home run on FanDuel at +410 odds.
- Time: 3:07 p.m. ET
- Where to watch: MLB.TV
📡 SBR Edge: Righty Express
De La Cruz has hit 20 of 30 home runs against right-handed pitching in 2026.
π₯ More home run predictions today
Home run pick: Christian Walker (+400)
The Astros are in a dogfight with the Rangers for the final playoff seed in the American League, so Walker should continue his plate production in a plus matchup today. He's hit 3 home runs in his past 5 contests.
The Astros' 1B has hit 18 of 28 home runs in away ballparks this year, including 2 at Sutter Health Park in this series. Winds will be blowing out at 6.6 mph at Sutter Health Park today.
This is already a hitter-friendly ballpark, so Walker's set up for his third home run of the series as a right-handed hitter against a struggling lefty.
Go to bet365 to bet on Walker's home run prop at +400 odds.
- Time: 3:05 p.m. ET
- Where to watch: MLB.TV
Home run pick: Munetaka Murakami (+375)
The White Sox have clinched a playoff berth, but Murakami continues to punish baseballs. The Japanese slugger has recorded 3 home runs in his previous 5 appearances.
Freeland has given up 6 home runs in his last 4 starts for the Rockies. This creates a great opportunity for Murakami in his final regular-season start at Rate Field.
Winds will be blowing into right field at 7.6 mph today. Murakami has hit 7 home runs against left-handed pitching in 166 plate appearances, while logging 20 of 35 home runs at Rate Field.
Go to DraftKings for the best number on Murakami's home run prop at +375 odds.
- Time: 3:10 p.m. ET
- Where to watch: MLB.TV
π Best home run parlay picks today
💵 Best MLB home run parlay today
- Elly De La Cruz (+404)
- Christian Walker (+358)
- Munetaka Murakami (+375)
Best odds: +10865 via DraftKings (0.10u -> 10.86u)
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