MLB Best Home Run Predictions Today: Best HR Props, Picks, Parlay & Odds For Saturday, Sept. 19
Saturday's 15-game MLB slate gives us another chance to find players with home run potential for my home run predictions today. I'm in a slump right now, and players are going yard the night after picking them, so we have to stay the course heading into Saturday's matchups.
My MLB home run picks begin with Alex Bregman. The Cubs' 3B is playing in a hitter-friendly ball park today at Great American Ball Park in Cincinnati, with 6 mph wind gusts blowing out. Bregman will face Nick Lodolo tonight. The Reds' southpaw pitcher has surrendered 7 home runs across his last 5 starts.
βΎ Home run predictions today: MLB HR picks & odds Sept. 19
See all of our expertsβ MLB picks based on the latest MLB odds.
| π£ Home run pick | π΅ Units | π Notes |
|---|---|---|
| Alex Bregman (+492 via DraftKings) | 0.25u β 1.23u | Lodolo has surrendered 7 home runs in his last 5 starts for the Reds. |
| Lawrence Butler (+550 via bet365) | 0.25u β 1.37u | Butler has recorded 5 home runs in September. |
| Luis Garcia Jr.(+560 via FanDuel) | 0.25u β 1.40u | 27 of Garcia's 30 home runs have been against right-handed pitching. |
π£ Best home run predictions & odds today
Home run pick: Alex Bregman (+492)
Bregman has a great opportunity to hit a home run for the second time in three appearances tonight. He's hit 3 home runs in September, while recording 7 home runs against left-handed pitchers in 138 at-bats this season.
Lodolo is dreadful. He's ranked in the 11th percentile for barrel percentage allowed (10.0), 14th in avg exit velo allowed (90.1 mph), and in the 29th percentile for hard-hit rate (40.9) this season. Bregman is a right-handed hitter against a struggling southpaw.
Bet Bregman's home run prop on DraftKings at +492 odds.
- Time: 6:40 p.m. ET
- Where to watch: MLB.TV
📡 SBR Edge: Homers Galore
Great American Ball Park has a shallow outfield and ideal conditions for home runs, which is why it's second in total home runs hit (231) in 2026.
π₯ More home run predictions today
Home run pick: Lawrence Butler (+550)
I had success backing Butler a few days ago, and I'll run right back to the lefty in today's road contest against Tanner Bibee. The Guardians' pitcher has allowed a career-high 28 home runs in 2026, including 3 across his last 5 starts.
Butler's mashed 13 of 17 home runs against right-handed pitching this year. He's also ranked 76th in hard-hit rate (45.0), while Bibee is allowing an 8.3 barrel percentage (35th) and a hard-hit percentage of 39.2 (41st) amongst MLB pitchers.
Butler's been red-hot in September, logging 5 home runs this month. Plus, 10 mph wind gusts are blowing into left field at Progressive Field tonight.
Head to bet365 to bet on Butler's home run prop at +550 odds.
- Time: 6:10 p.m. ET
- Where to watch: MLB.TV
Home run pick: Luis Garcia Jr. (+560)
The Yankees' trade for Garcia has panned out nicely. The left-handed hitter has hit 27 of 30 home runs against right-handed pitching this season.
Now, Garcia will face Brandon Pfaadt, who has surrendered 6 home runs across his previous 5 starts for the Diamondbacks. Pfaadt is struggling on the mound right now, giving up 17 hits and 9 earned runs in his previous 2 outings.
Garcia is a monster at the plate. He's ranked 94th in xSLG (.500) this year, while also sitting above the 83rd percentile in barrel percentage (12.7) and hard-hit percentage (47.2).
Go to FanDuel for the best line on Garcia's home run prop at +560 odds.
- Time: 8:10 p.m. ET
- Where to watch: MLB.TV
π Best home run parlay picks today
💵 Best MLB home run parlay today
- Alex Bregman (+450)
- Lawrence Butler (+520)
- Luis Garcia Jr. (+560)
Best odds: +22406 via FanDuel (0.10u -> 22.4u)
📃 Affiliate disclosure
Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
Related Articles
