Astros vs. Rays Prediction & Picks: MLB Odds for Saturday, Sept. 12

My Astros vs. Rays prediction breaks down the best bet and player prop I'm betting today.
Houston Astros shortstop Jeremy Pena (3) smiles as we break down our Astros vs. Rays prediction.
Pictured: Houston Astros shortstop Jeremy Pena (3) smiles as we break down our Astros vs. Rays prediction. Photo by Thomas Shea / Imagn Images.
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My Astros vs. Rays prediction expects Houston to bounce back today after Junior Caminero hit a walk-off home run in Friday's series opener.

Peter Lambert and Ian Seymour square off in the second game of the three-game set, with Yordan Alvarez (ankle) potentially returning for the Astros. My MLB picks fade the Rays as a -144 betting favorite, with first pitch from Tropicana Field in St. Petersburg, Fla., set for 6:10 p.m. ET (MLB.TV).


⚾ Astros vs. Rays picks & odds today

See all of our experts’ MLB picks based on the latest MLB odds.

⚾ Pick πŸ’΅ Units πŸ“ Notes
Astros ML (+122 via FanDuel) 1.64u β†’ 2u Lambert has allowed 2 or fewer ER in 8 of his 10 starts since the All-Star break.
Jeremy Pena Over 1.5 bases (+139 via DraftKings) 1.08u β†’ 1.5u Seymour throws primarily fastballs and offspeed pitches vs. RHB, and Pena has a .508 and .408 xSLG vs. those pitch types, respectively.

Total wagered: 2.72 units | Max profit: 3.5 units

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πŸ’° Astros vs. Rays prediction & best bet

Follow all of our MLB analysis and expert predictions for baseball season.

Astros ML (+122)

The Rays were somewhat lucky to win Friday night, needing Caminero to hit a walk-off home run in the ninth inning.

The Astros respond today with Lambert, whose season-long stats don't look great, but he's been better recently. Lambert has allowed two or fewer earned runs in eight of his 10 starts since the All-Star break. And with Alvarez potentially returning today, the Astros have a better shot at pulling off the upset than these odds suggest.

Astros ML (+122) at FanDuel is the best line available among the top MLB betting sites.

💵 More MLB expert picks today

Looking for more? Dive into Matt MacKay's home run predictions or Phil Wood's best NRFI bets today.


πŸ”₯ Best Astros vs. Rays player prop bet

Jeremy Pena Over 1.5 bases (+139)

Pena has been a little worse than expected lately - he's only gone over this line in two of his last four games - but he has a favorable pitching matchup today and will likely take advantage.

He faces Seymour, who throws 41.7% fastballs and 32.8% offspeed pitches to right-handed batters. Luckily for Pena, he has an expected slugging percentage of .508 and .408 against those pitches, respectively.

I'd be surprised if Pena didn't at least hit a double today. Jeremy Pena Over 1.5 bases (+139) at DraftKings is the best line available among the top sports betting sites.

📡 SBR Edge: Lefty Fastballs

Pena has a .330 expected batting average against fastballs from left-handed pitchers, which is Seymour's most-used pitch type when facing right-handed batters.


πŸ“Š Live Astros vs. Rays odds


πŸš‘ Astros vs. Rays injuries


πŸ“Ί How to watch Astros vs. Rays

  • Date: Saturday, Sept. 12
  • First pitch: 6:10 p.m. ET
  • Ballpark: Tropicana Field (St. Petersburg, Fla.)
  • TV: MLB.TV
  • Astros starter: Peter Lambert (8-8, 3.67 ERA)
  • Rays starter: Ian Seymour (9-6, 4.33 ERA)