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Payton Thorne #10 of the Michigan State Spartans plays against the Ohio State Buckeyes at Spartan Stadium on Oct. 8.
Payton Thorne #10 of the Michigan State Spartans plays against the Ohio State Buckeyes at Spartan Stadium on Oct. 8. Gregory Shamus/Getty Images/AFP

Michigan State is still searching for its first Big Ten win (0-3) of the season entering Saturday's home affair against Wisconsin. Check out our top Wisconsin-Michigan State picks below.

The Michigan State Spartans were drubbed 49-20 on their home field by Ohio State last week. They failed to cover even a 27.5-point spread as underdogs. That marked a third straight loss in Big Ten play and fourth straight loss overall.

Wisconsin enters Week 7 at 3-3 overall and 1-2 against conference opponents. That win came by a 42-7 margin over Northwestern last week.

Here are our top picks for the college football matchup between Michigan State and Wisconsin (odds via DraftKings Sportsbook, FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Wisconsin vs. Michigan State Odds

Wisconsin vs. Michigan State Picks

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Wisconsin vs. Michigan State ATS Pick

Wisconsin -7.5 (-104) ★★★★

The Badgers have three losses this season, but against a 5-1 Illinois, an undefeated Ohio State, and a 4-2 Washington State with losses to only ranked teams. Wisconsin has racked up 191 total points on offense this season.

The Spartans may have 155 points this season, but have just 40 in their last three games and have lost by a margin of 11 points or more in four straight games this season.

Under new head coach Jim Leonhard after Paul Chryst’s firing, the Badgers put up 515 yards of offense with Graham Mertz throwing for a career-high 299 yards for five touchdowns. With the Spartans allowing 292 yards in the air per game, they’re in trouble against Wisconsin’s passing offense.

Wisconsin vs. Michigan State O/U Pick

Under 46.5 (+126) ★★★

Michigan State is averaging 26.2 points per game this season and Wisconsin is averaging 31.8, good for 58 points per game between the two teams.

But in their last three meetings, the two have failed to score more than 38 points between them. Michigan State scored just six points against Wisconsin in the last two meetings while Wisconsin has scored 30-plus points in each meeting.

With Michigan State failing to score more than 20 points in their last three games, the offense will be pushed again against a Wisconsin team that has allowed less than 17 points against four times this season.

Wisconsin vs. Michigan State Prop Pick

Michigan State Over 3.5 1st-quarter points (+115) ★★★★

Despite their less-than-ideal results in their last two games, Michigan State has managed to score 13 first-half points against each of their last two opponents, including seven points in the first quarter of each game.

Only on two occasions – their losses to Washington and Minnesota – has Michigan State failed to score at least seven points in a first quarter.

Wisconsin has allowed seven or more points in the first quarter only twice this season, but the occasion has happened in two of their last three games, allowing Illinois and Ohio State to score in the first quarter.

Where to Bet on Wisconsin vs. Michigan State Picks

Wisconsin-Michigan State picks made on 10/12/2022 at 3:17 p.m.