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John Rhys Plumlee of the UCF Knights looks to throw a pass in the first quarter against the Cincinnati Bearcats.
John Rhys Plumlee of the UCF Knights looks to throw a pass in the first quarter against the Cincinnati Bearcats. Julio Aguilar/Getty Images/AFP.

The UCF Knights will need some help to make the AAC Championship Game, but they must first get past the South Florida Bulls. Read on for our top UCF-South Florida college football picks.

The Bulls head into the final week of the season still looking for their first win over an FBS opponent. They'll face a tough challenge against UCF, the No. 25 team in the country.

The Knights are coming off a home loss to the Navy Midshipmen. They now need to win and get some help to earn a spot in the American Athletic Conference championship game.

Here are our top picks for the UCF-South Florida clash in Week 13 (odds via DraftKings Sportsbook; Pick confidence is based on a 1-to-5-star scale).

Check out our top college football picks for Week 13!

UCF vs. South Florida Odds

UCF vs. South Florida Picks

UCF vs. South Florida ATS Pick

UCF -19.5 (-110) ★★★★

Despite being 1-10 overall, the Bulls are 4-7 against the spread in 2022. They very nearly covered during their last two home games, missing by a half-point against the SMU Mustangs and two points against the Tulane Green Wave.

However, the Knights are going to take out all their frustrations on a bad team in Week 13 after they lost control of their fate against Navy. The Bulls have allowed 40-plus points in five consecutive contests. South Florida may score into the 20s, but it won’t be enough to cover this spread.

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UCF vs. South Florida O/U Pick

Over 68 (-110) ★★★

This is a really high number, but UCF boasts a solid offense, and the Bulls' defense is horrible. But the Over will cash because of more than just that matchup. The Bulls have scored 20-plus points in seven consecutive games and 10 of their 11 contests.

With the Knights slated to produce a huge day offensively, the Bulls will just need to crack 20 again for this Over to hit. The Knights have allowed their opponents to reach that number in four of their last five games.

UCF vs. South Florida Prop Pick

UCF team total Over 44.5 (-120) ★★★

The Bulls are giving up an average of 40.7 points per game, and they've allowed opponents to score 40-plus points eight times in 2022. That includes four opponents that cleared 44.5 points.

The Knights have only gone past this number twice all season, but they're about to face one of the worst-scoring defenses in the entire NCAA. You could take the safe route and back the Bulls to score 40-plus points through PointsBet, but the price is -220. That’s a bit steep. Take the Knights to go Over 44.5 in a game when they may clear 50.

Where to Bet on UCF-South Florida Picks

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UCF vs. South Florida picks made 11/23/2022 at 7:43 p.m. ET