College Football Predictions Today: Best Week 11 Bets & Odds
Last Updated: November 7, 2025 9:27 PM EST • 2 minute read X Social Google News Link
Our college football Week 11 predictions continue with a loaded Saturday that will impact on conference championship races and the College Football Playoff rankings.
This week, our college football picks cover the College GameDay matchup between BYU and Texas Tech, Oregon's toughest game since losing to Indiana, a ranked SEC matchup, LSU's first game after firing Brian Kelly, and much more.
🏈 College football predictions: Week 11
Here are all of our college football expert picks for Week 11, which we'll update throughout the week.
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💰 College football odds & expert picks: Saturday
Here are the latest college football odds for every Week 11 game via the best college football betting sites, which update live in real time.
📊 Auburn vs. Vanderbilt odds
- Date: Saturday, Nov. 8
- Kickoff: 4 p.m. ET
- Location: FirstBank Stadium (Nashville)
- How to watch: SEC Network
📊 LSU vs. Alabama odds
- Date: Saturday, Nov. 8
- Kickoff: 7:30 p.m. ET
- Location: Bryant-Denny Stadium (Tuscaloosa, Ala.)
- How to watch: ABC
🔮 LSU vs. Alabama prediction
🐯 LSU +10 (-110)
I am not declaring that the sky is falling on the LSU program, even though it will be looking for a new head coach this offseason, given that it has lost two road games to top-10 teams by a combined 12 points. Alabama has a top-six defense in drive efficiency surrendered, but LSU’s is in the ballpark, ranked 42nd, and even better at No. 4 on a per-play basis.
-via Mike Spector's LSU vs. Alabama prediction
📊 Navy vs. Notre Dame odds
- Date: Saturday, Nov. 8
- Kickoff: 7:30 p.m. ET
- Location: Notre Dame Stadium (Notre Dame, Ind.)
- How to watch: NBC, Peacock
🔮 Navy vs. Notre Dame early prediction
⚓️ Navy +27.5 (-110)
After opening as a 25.5-point favorite, Notre Dame has gotten out to 27.5, which is far too much for me. While the Irish have a sizeable advantage over Navy, the Midshipmen’s slow-paced option offense makes covering just under four touchdowns very difficult. It’s something Notre Dame has done recently in this rivalry, but it’s not something this year’s team has shown the ability to do.
-via Isaiah Sirois's Navy vs. Notre Dame prediction
💡 College football expert picks: Week 11
- College football picks against the spread Week 11
- College football predictions for every top 25 game in Week 11
- College football player props Week 11
- College football best bets Week 11
- College football anytime touchdown scorer predictions Week 11
- Big Ten best bets Week 11
- SEC best bets Week 11
- College football Week 11 betting report
- Heisman Trophy power rankings Week 11
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