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Quarterback D.J. Uiagalelei of the Clemson Tigers looks to pass against the Wake Forest Demon Deacons.
Quarterback D.J. Uiagalelei of the Clemson Tigers looks to pass against the Wake Forest Demon Deacons. Jacob Kupferman/Getty Images/AFP.

The ACC title game features the Clemson Tigers and North Carolina Tar Heels. The No. 9 and No. 23 teams in the country, respectively clash in Charlotte, NC. Read on for our top Clemson-North Carolina college football picks.

The Tigers' streak of six consecutive ACC titles ended last season after they failed to win the Atlantic Division and even qualify for the championship game. For the Tar Heels, this is their first appearance in the title game since 2015. 

Neither team has been playing well coming into this game, so who has the advantage on Saturday?

Here are our Clemson-North Carolina college football picks for Week 14 (odds via DraftKings Sportsbook, FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Check out our college football best bets and all of our top picks for Week 14!

Clemson vs. North Carolina Game Info

Date: Saturday, Dec. 3, 8 p.m. ET
Location: Bank of America Stadium, Charlotte, NC
Weather: 38 degrees, 17% chance of precipitation, 7-mph winds

Clemson vs. North Carolina Odds

Clemson vs. North Carolina Analysis

The consensus opening spread of Clemson -7.5 has held steady through the week despite 54% of the tickets accounting for 59% of the handle on UNC.

Meanwhile, the Over/Under opened at a consensus line of 62 but has ticked up to 64 as of Saturday morning with 76% of the tickets making up 81% of the handle on the Over.

Check out Bet365's "Win and You're In" boost for this weekend's slate of games.

Clemson vs. North Carolina Picks

Clemson vs. North Carolina ATS Pick

Clemson -7.5 (-106) ★★★★

This line is very interesting. The Tigers are coming off a very public and shocking loss to the South Carolina Gamecocks, so it's weird to see them favored by more than a touchdown. Perhaps it's just because the Tar Heels lost their last two games. Either way, it seems like bettors are being baited by oddsmakers to take the Tar Heels in this one. 

The Tigers may have lost to South Carolina, but that team has been pesky all season. Prior to that, Clemson took care of Miami and Louisville with ease. 

Meanwhile, the Tar Heels have lost their last two games, and their previous two wins were by a combined five points over Wake Forest and Virginia. 

Clemson vs. North Carolina O/U Pick

Over 63 (-110) ★★★

The Clemson defense may only be giving up 20.9 points per game, but the Tigers have not looked good down the stretch. They gave up 31 points last week to the Gamecocks, and 35 in their previous loss to Notre Dame.

The Tar Heels’ offense is averaging 37.1 points per game, and even if they’ve only managed a combined 44 points in their last two games, they’re going to have plenty of opportunities to score in this one.

Yet, even if the Tar Heels continue to struggle, Dabo Sweeney is going to have his team ready to destroy the Tar Heels if possible, especially after last week’s performance. Clemson is averaging nearly five touchdowns per game, while the Tar Heels are allowing over 30 points per. That's a recipe for disaster for North Carolina.

Clemson vs. North Carolina Prop Pick

Clemson Over 36.5 points (-105) ★★★★

Six of the last seven times that the Tigers have made the ACC championship game, they have scored more than 35 points. The only time that they didn’t was in 2020 when they scored 34 against Notre Dame. Their average margin of victory in those games was greater than 25 points. That means when Clemson starts scoring, the team doesn’t stop in championship games.

The North Carolina defense hasn’t allowed 35 points in a game since Duke hit that mark back on Oct. 15. Yet, a lot of that success has to do with the lack of offensive talent that the Tar Heels have faced. The best offense they faced in the last six games was Wake Forest, and the Demon Deacons put up 34 points. 

Where to Bet on Clemson vs. North Carolina

Check out our best sportsbooks:

Clemson-North Carolina picks made 12/1/2022 at 8:15 a.m. ET