Alabama vs. Vanderbilt Prediction: Week 11 Odds, Picks & Best Bet (Nov. 14)
One of the nation's top-ranked programs hits the road Saturday to potentially flex its muscle as I make my Alabama vs. Vanderbilt prediction.
No. 3 Alabama just handed LSU its first home loss of the season in Week 10 and will now look to keep rolling against Vanderbilt, which just earned its first SEC win. Alabama is a 17-point betting favorite, with kickoff from FirstBank Stadium in Nashville, Tenn., set for 12:45 p.m. ET (SEC Network).
Alabama vs. Vanderbilt picks & predictions
See all of our experts' college football picks for Week 11 based on the latest college football odds.
| Pick | Odds | Bet size |
|---|---|---|
| Alabama -17 | -110 via BetMGM | 1.1 units to profit 1 unit |
| Over 50.5 | -108 via DraftKings | 2.16 units to profit 2 units |
Picks submitted: Nov. 12 at 10 a.m. ET. Odds subject to change.
Total wagered: 3.26 units | Profit if all picks win: 3 units
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Alabama vs. Vanderbilt prediction & best bet
Check out all of our college football predictions for more analysis across this week's slate.
Over 50.5 (-108 via DraftKings)
All signs point toward a lot of points in this SEC tilt. The weather will be sunny and calm, with the worst scoring defense in the SEC on the field against Alabama's top-20 offense, averaging over 37 points per game.
Keelon Russell has been red hot for the Crimson Tide in the passing attack. Alabama's quarterback has thrown for over 500 combined yards and six touchdowns in his last two outings, and now, Russell faces a Vanderbilt secondary allowing three of its past five conference opponents to log either 250+ passing yards or multiple passing touchdowns.
The Commodores are even worse at defending the run. Vanderbilt has allowed at least 4.4 yards per carry against every SEC opponent it has faced in 2026, excluding its 25-23 win over a short-handed Mississippi State offense in Week 10.
Alabama may hit the Over by itself in Nashville on Saturday. Vanderbilt only has to score 10 points, which it has cleared in each of its games this season.
📡 SBR Edge: Commodore Cushion
Vanderbilt has only forced one turnover in its previous three appearances, while allowing 31 or more points against four of six conference opponents.
Alabama routs Vanderbilt with offensive burst
Russell stays hot for Alabama's offense in this game, leaning on his legs to exploit a vulnerable Vanderbilt run defense. The Crimson Tide's run game gets going again in this matchup, with Daniel Hill and Trae'shawn Brown making the most of their carries.
It's going to be a long day for Vanderbilt, regardless of which play is called by Alabama's offense. Ultimately, Alabama routs Vanderbilt on the road, scoring at least 31 points for a third consecutive outing.
Play to: Over 51.5
Score prediction: Alabama 45, Vanderbilt 13
Live Alabama vs. Vanderbilt odds
See the latest odds movement and more on our Alabama vs. Vanderbilt matchup page.
Alabama vs. Vanderbilt opening odds
- Moneyline: Alabama -1200 | Vanderbilt +900
- Spread: Alabama -19.5 (-105) | Vanderbilt +19.5 (-115)
- Over/Under: Over 54.5 (-102) | Under 54.5 (-118)
Alabama vs. Vanderbilt weather
The forecast at kickoff from FirstBank Stadium calls for 45 degrees with 6-mph winds and a 0% chance of precipitation. Sunny skies, minimal wind, and no rain create perfect conditions for this game.
Latest Alabama vs. Vanderbilt injuries
Alabama:
- None
Vanderbilt:
- None
How to watch Alabama vs. Vanderbilt: Week 11
- Date: Saturday, Nov. 14
- Kickoff: 12:45 p.m. ET
- Location: FirstBank Stadium (Nashville, Tenn.)
- TV/Streaming: SEC Network, Fubo
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