Rams vs. Eagles Prediction: Week 4 Odds, Picks & Best Bet
Last Updated: October 4, 2026 9:38 AM EDT • 2 minute read X Social Google News Link
My Rams vs. Eagles prediction focuses on how the Eagles' offense will match up with the Rams' defense. The Rams will be without Myles Garrett, Aaron Donald, and Jaylen Watson, but I still give them the advantage today over an offense averaging the ninth-fewest yards per game.
With Puka Nacua returning for L.A. this week, the Rams are a 3.5-point betting favorite. Kickoff from Lincoln Financial Field in Philadelphia is set for 1 p.m. ET (FOX).
🏈 Rams vs. Eagles picks & predictions
See all of our experts' NFL picks for Week 4 based on the latest NFL odds.
| Pick | Bet size |
|---|---|
| Rams -3.5 (-112 via BetMGM) | 2 units |
| Under 42.5 (-108 via BetMGM) | 1.5 units |
Total wagered: 3.5 units | Max profit: +3.18 units
💰 Rams vs. Eagles prediction & best bet
Rams -3.5 (-112 via BetMGM)
On Monday, the Eagles lost 27-7 to Case Keenum and the Bears. In the second half, the Eagles managed just 52 yards on five drives. The results of those drives were three punts, an interception, and a turnover on downs.
This week, Jalen Hurts, Saquon Barkley, and the rest of the Eagles' struggling offense will attempt to find success against a Rams defense that is allowing just 4.6 yards per play. That's the second-best mark in the league.
The Rams are allowing the fewest yards per game, and the pass defense ranks fourth in the league. With Hurts completing just 64.4% of his passes and averaging only 7.1 yards per attempt, the Rams have the clear advantage in this matchup.
📡 SBR Edge
The Eagles have managed just 76 rush attempts thus far, which ranks 24th in the league. This emphasizes how out of sync this offense is, as they ranked in the top 11 in rush attempts each of the last five years.
Eagles stand no chance against the Rams' passing game
Matthew Stafford has been without Nacua for two weeks, and yet the Rams have scored 54 points, and they rank second in the league in passing yards per game. Now, Nacua returns, and even if he plays limited snaps, as some reports suggest, the Rams' attack is still going to overpower the Eagles' secondary.
The Eagles rank eighth in passing yards allowed per game this season. However, two of the three quarterbacks they faced were Keenum and Cam Ward. Though Stafford threw two interceptions last week, he was also sacked four times. The Eagles have only three sacks all season, and without any pressure on him, Stafford will carve up this defense.
Score prediction: Rams 24, Eagles 10
📊 Rams vs. Eagles odds
See the latest NFL odds for every Week 4 matchup.
Rams vs. Eagles opening odds
- Moneyline: Rams -120 | Eagles +100
- Spread: Rams -1.5 (-110) | Eagles +1.5 (-110)
- Over/Under: Over 47.5 (-110) | Under 47.5 (-110)
📺 How to watch Rams vs. Eagles: Week 4
- Date: Sunday, Oct. 4
- Kickoff: 1 p.m. ET
- Location: Lincoln Financial Field (Philadelphia)
- TV: FOX
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Philip Wood X social