Rams vs. Cardinals Prediction: Week 10 Odds, Picks & Best Bet (Nov. 15)
Los Angeles' defense will need to carry the load Sunday, as my Rams vs. Cardinals prediction prioritizes the Under in this NFC West matchup.
Kickoff from State Farm Stadium in Phoenix is set for 4:05 p.m. ET (CBS), with the Rams priced as a 9.5-point betting favorite.
Rams vs. Cardinals picks & predictions
See all of our experts' NFL picks for Week 10 based on the latest NFL odds.
| Pick | Odds | Bet size |
|---|---|---|
| Rams -9.5 | -110 via BetMGM | 0.5 units to profit 0.46 units |
| Under 39.5 | -110 via BetMGM | 1 unit to profit 0.91 units |
Picks submitted: Nov 12 at 9 a.m. ET. Odds subject to change.
Total wagered: 1.5 units | Profit if all picks win: 1.37 units
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Rams vs. Cardinals prediction & best bet
Under 39.5 (-110 via BetMGM)
A decimated Los Angeles pass-catcher group limits the Rams' scoring potential in this matchup, as we've seen in recent weeks. The Rams will be without Puka Nacua and Davante Adams, while three of their tight ends are also on the injury report. Three of the last four Rams games have gone Under their projected total, including last month's loss to the Cardinals that totaled just 34 points.
The Rams have had some massive offensive performances versus Arizona in recent years, but they simply don't have the horses right now to run up the score this Sunday.
The best sports betting sites are aligned on a 39.5 total, with BetMGM offering the top value at -110 odds. I would back the Under on a total as low as 37.5.
📡 SBR Edge
The Rams are allowing an average of 15 points per game since Week 6.
Beck's baptism by fire
Cardinals rookie quarterback Carson Beck is making his first career start this Sunday against a Rams defense that ranks fifth in EPA/play.
He'll have one of the league's worst skill-position groups at his disposal as Myles Garrett and Aaron Donald bear down on him. The Cardinals won't contribute much to the scoring here in a low-scoring Rams victory.
Play to: Under 37.5 (-105), pass at Under 36.5.
Score prediction: Rams 23, Cardinals 13
Live Rams vs. Cardinals odds
See the latest odds movement and more on our Rams vs. Cardinals page.
Rams vs. Cardinals opening odds
- Moneyline: Rams -385 | Cardinals +290
- Spread: Rams -8.5 (-105) | Cardinals +8.5 (-115)
- Over/Under: Over 47.5 (-110) | Under 47.5 (-110)
Rams vs. Cardinals weather
The Cardinals' State Farm Stadium has a retractable roof, so the weather won't affect this matchup.
Latest Rams vs. Cardinals injuries
How to watch Rams vs. Cardinals: Week 10
- Date: Sunday, Nov. 15
- Kickoff: 4:05 p.m. ET
- Location: State Farm Stadium (Phoenix)
- TV/Streaming: CBS, Fubo
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