Dolphins vs. Colts Prediction: Week 10 Odds, Picks & Best Bet (Nov. 15)
My best Dolphins vs. Colts prediction highlights how the absence of Malik Willis won't actually have that much of a negative impact on the Dolphins in this matchup. Kyle McCord will make his first NFL start, but I don't expect him to have to do much, as the Dolphins lean on their rushing attack against one of the worst run defenses in football.
The Colts are favored by 3.5 points ahead of Sunday's 1 p.m. ET game at Lucas Oil Stadium in Indianapolis. The game will air on CBS and stream on Paramount+.
Dolphins vs. Colts picks & predictions
See all of our experts' NFL picks for Week 10 based on the latest NFL odds.
| Pick | Odds | Bet size |
|---|---|---|
| Dolphins +3.5 | -102 via DraftKings | 1.5 units to profit 1.47 units |
| Under 38.5 | -115 via bet365 | 1.5 units to profit 1.3 units |
Picks submitted: Nov. 13 at 4 p.m. ET. Odds subject to change.
Total wagered: 3 units | Profit if all picks win: 2.77 units
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Dolphins vs. Colts prediction & best bet
Dolphins +3.5 (-102 via DraftKings)
McCord playing in his first regular-season game is the only thing working against the Dolphins on Sunday. I don't expect McCord to need to do much, as the Colts rank 30th in rushing yards allowed per game (137.0) and 29th in yards allowed per carry (4.9). Ollie Gordon II is averaging 4.3 yards per carry this season, and he's recorded two 100-yard games.
The Dolphins' defense has also been really good this season. They just allowed 19 points and one touchdown to the Lions, and they're currently 13th in total defense, allowing just 326.1 yards per game. The Dolphins have been particularly good against the run, allowing just 3.8 yards per carry.
Jonathan Taylor has been good this season, but he's yet to rush for 100 yards in a game, and he's only averaging 4.1 yards per carry. Even against the Cowboys' 31st-ranked run defense, he managed just 46 yards on 13 carries, with his longest run only seven yards.
📡 SBR Edge
McCord couldn't ask for a much better defense to make his first start against, as the Colts rank 30th in points allowed per game (27.7), giving up at least 26 points in six of their nine games.
Can the Dolphins win the turnover battle?
The Dolphins have a -3 turnover margin, but have only given away the ball 10 times this season. That's tied for the 13th-fewest in the league. Obviously, I don't know what to expect from McCord in this game, but I expect the Dolphins to run a safe offense that doesn't ask him to make many throws. If that's the case, then fumbles are the only real concern for the Dolphins, but they only have four this season.
Meanwhile, the Colts have a turnover margin of -11, tied for the worst in the league. They have turned the ball over 17 times while forcing just six turnovers, the second-lowest total in the league.
The Dolphins only have seven takeaways this season, but five of those turnovers are interceptions. I'd be shocked if they didn't pick off at least one pass, as Daniel Jones has thrown an interception in all but one game this season.
Play to: Dolphins +3.5 at -125
Score prediction: Dolphins 17 Colts 13
Live Dolphins vs. Colts odds
See the latest odds movement and more on our Dolphins vs. Colts page.
Dolphins vs. Colts opening odds
- Moneyline: Dolphins +100 | Colts -120
- Spread: Dolphins +1.5 (-112) | Colts -1.5 (-108)
- Over/Under: Over 43.5 (-110) | Under 43.5 (-110)
Dolphins vs. Colts weather
This game will be played in a dome.
Latest Dolphins vs. Colts injuries
How to watch Dolphins vs. Colts: Week 10
- Date: Sunday, Nov. 15
- Kickoff: 1 p.m. ET
- Location: Lucas Oil Stadium (Indianapolis)
- TV/Streaming: CBS/Paramount+
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