NFL Moneyline Picks for Week 10: Best Bets to Win Every Game
Favorites have a 91-44-1 record (67.3%) as I offer my NFL moneyline picks for Week 10. While I've picked a winner for each Week 10 game, I'm featuring the Washington Commanders, Carolina Panthers, and Green Bay Packers.
The Commanders look to make up for the missed opportunity against the G-Men last time around, and the Panthers and Packers will fancy their chances in divisional games against the New Orleans Saints and Minnesota Vikings, respectively.
NFL moneyline picks: Week 10
See all of our experts' NFL picks for Week 10 based on the latest NFL odds; pick confidence based on a 1-to-5-star scale.
| Matchup | Pick | Confidence |
|---|---|---|
| 49ers vs. Cowboys | 49ers (-205) | ⭐⭐⭐⭐⭐ |
| Rams vs. Cardinals | Rams (-430) | ⭐⭐⭐⭐⭐ |
| Bills vs. Jets | Bills (-460) | ⭐⭐⭐⭐⭐ |
| Steelers vs. Bengals | Bengals (-184) | ⭐⭐⭐⭐ |
| Patriots vs. Lions | Lions (-152) | ⭐⭐⭐⭐ |
| Vikings vs. Packers | Packers (-172) | ⭐⭐⭐⭐ |
| Texans vs. Browns | Texans (-240) | ⭐⭐⭐⭐ |
| Chiefs vs. Falcons | Chiefs (-180) | ⭐⭐⭐⭐ |
| Dolphins vs. Colts | Colts (-200) | ⭐⭐⭐⭐ |
| Seahawks vs. Raiders | Seahawks (-300) | ⭐⭐⭐⭐ |
| Commanders vs. Giants | Commanders (+114) | ⭐⭐⭐ |
| Panthers vs. Saints | Panthers (+118) | ⭐⭐⭐ |
| Jaguars vs. Titans | Jaguars (-590) | ⭐⭐⭐ |
| Chargers vs. Ravens | Ravens (-225) | ⭐⭐⭐ |
My best NFL Week 10 moneyline bets
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 10.
Commanders (+114 via FanDuel) vs. Giants ⭐⭐⭐
While all signs point to J.J. McCarthy getting the nod, I'm not confident he'll be at his best after a short week and a hip injury in Week 9. Meanwhile, Jayden Daniels has been solid despite losing two of the previous three. Those two losses came against the Los Angeles Rams and the San Francisco 49ers. Daniels has seven TD passes and no interceptions, while McCarthy has one TD and one pick.
The Commanders threw away a golden opportunity to beat the Giants in Week 5, blowing a 14-point lead and botching their last chance to win. They were the better team for most of the game, and I expect a similar scenario in Week 10, this time with the Commanders making it count.
More Week 10 picks
Panthers (+118 via BetMGM) vs. Saints ⭐⭐⭐
The Panthers struggled offensively in the last three games, but I'm not letting that deter me, as they faced three teams -- Tampa Bay Buccaneers (1st), Green Bay Packers (5th), and Denver Broncos (9th) -- among the top 10 in defensive DVOA. The New Orleans Saints' 30th-ranked stop unit pales in comparison.
Despite not scoring more than 21 points against those teams, the Panthers offense remains 13th via DVOA. Meanwhile, the Saints lost four of the previous six and were fortunate to beat the Cleveland Browns at home in overtime in Week 9.
Vikings vs. Packers (-172 via FanDuel) ⭐⭐⭐
Kirk Cousins' return to Minnesota will invariably make this matchup between NFC North rivals more interesting and harder to call. However, Cousins joins the Vikings with little time to prepare, and while he's familiar with goings-on in Minnesota, the veteran quarterback faces a Green Bay Packers team that is flying.
The Packers have won five of the previous six and exploded for 45 points on the road in Week 9 against the New England Patriots. Jordan Love is playing some of his best football, with 10 TD passes and three picks in the last five games. And while their defense hasn't been as good as the Vikings' stop unit, the discrepancy isn't massive.
Green Bay's defense has allowed more than 20 points once in the last six games.
More Week 10 predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 10.
📃 Affiliate disclosure
Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
Related Articles
