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Kadarius Toney of the Kansas City Chiefs reacts after catching a pass against the Jacksonville Jaguars.
Kadarius Toney of the Kansas City Chiefs reacts after catching a pass against the Jacksonville Jaguars. Photo by Jason Hanna/Getty Images via AFP.

The Kansas City Chiefs and Los Angeles Chargers meet for the second time this season, with the latter essentially needing a win to keep its AFC West hopes alive. Check out our Week 11 Chiefs-Chargers same-game parlay picks.

The Chiefs survived their first matchup against the Chargers this season thanks to a miraculous 99-yard Jaylen Watson interception return for a touchdown.

Will the Chiefs’ offense find more explosiveness in the rematch on the road?

Here are my same-game parlay picks for the Week 11 Sunday Night Football matchup between the Chiefs and Chargers (odds via FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Chiefs vs. Chargers Odds

Chiefs vs. Chargers Week 11 Same-Game Parlay Picks

  • Chiefs -5.5 (-105)
  • Isiah Pacheco 60+ rushing yards (+130)
  • Kadarius Toney Over 53.5 receiving yards (-110)

Combined Odds: +509

Same-Game Parlay Predictions for Chiefs vs. Chargers

Chiefs -5.5 (-105) ★★★★

The Chiefs’ offense has been far more dominant on the road this season than at home. Outside of an inexplicable poor game at Indianapolis early in the year, Kansas City has posted road scoring outputs of 44 at Arizona, 41 at Tampa, and 44 at San Francisco.

Patrick Mahomes’ road prowess this season has led to a 3-1 record against the spread for the Chiefs in away games. On the flip side, the Chargers are 1-3 ATS at home this season.

Los Angeles has struggled offensively of late, averaging fewer than 20 points per game over the last four weeks. Another similar output this week simply won’t be enough to keep pace with Kansas City.

FanDuel offers the more favorable juice on the Chiefs at -105 odds on the -5.5 spread compared to -115 on Chiefs -5.5 at DraftKings Sportsbook.

Pacheco 60-plus rushing yards (+130) ★★★★

Though it’s been impossible this season to guess which Kansas City running back would be featured in an offense that doesn’t tend to lean on the run as it is, there were signs last week that the Isiah Pacheco takeover is imminent.

In Week 10 against Jacksonville, Pacheco drew 16 of the team’s 18 running back carries, logging a season-high 82 rushing yards. On the field for just four offensive snaps, Clyde Edwards-Helaire seems to have been phased out almost entirely.

The Chargers have one of the worst run defenses in the NFL, allowing 146.8 rushing yards per game. Los Angeles ranks 29th in run defense DVOA on the season, which makes this team a matchup you want to target on the ground.

Neither DraftKings nor FanDuel offers a standard rushing line for Pacheco, but FanDuel’s Alternate line of 60-plus yards at +130 odds is juicier than the Over 59.5 (+115) at DraftKings.

Toney Over 53.5 receiving yards (-110) ★★★

Kadarius Toney looked good for the Chiefs last week against the Jaguars, scoring his first-ever NFL touchdown on four receptions and 57 receiving yards. His role should be expanded on Sunday night as JuJu Smith-Schuster and Mecole Hardman are out for this game. Now that he’s healthy and integrated, I’m looking for the Chiefs to maximize Toney’s unique skill set.

Toney is set up for a big night. My only concern would be that too much of his production could come on the ground, so we’re hoping for more pop-passes than handoffs from Mahomes for Toney to get credit for all of his yardage.

The most comparable Toney line at DraftKings is Over 49.5 receiving yards at -125. That option puts the combined parlay odds at +450 at DraftKings, making FanDuel the preferred option for this build.

Where to Bet Chiefs-Chargers Same-Game Parlay Picks

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Chiefs-Chargers same-game parlay picks made on 11/20/2022 at 12:59 p.m. ET