Bills vs. Jets Prediction: Week 10 Odds, Picks & Best Bet (Nov. 15)

We break down Bills vs. Jets and make our best bet for the game, with a look at the spread, total, and predicted final score.
Josh Allen throwing a pass as we offer our Bills vs. Jets prediction for Nov. 15.
Pictured: Josh Allen throwing a pass as we offer our Bills vs. Jets prediction for Nov. 15. Photo by Jeffrey Becker via Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

Teams on opposing trajectories meet Sunday, and I'm backing Joe Brady and Co. in my Bills vs. Jets prediction.

Looking for their fifth straight victory, the AFC East-leading Bills are a 7.5-point betting favorite. The Jets enter on a four-game losing streak. Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 1 p.m. ET (CBS).


Bills vs. Jets picks & predictions

See all of our experts' NFL picks for Week 10 based on the latest NFL odds.

Pick Odds Bet size
Bills -7.5 +100 via FanDuel 1 unit to profit 1 unit
Over 50.5 -120 via FanDuel 0.5 units to profit 0.42 units 

Picks submitted: Nov. 13 at 8 a.m. ET. Odds subject to change.

Total wagered: 1.5 units | Profit if all picks win: 1.42 units

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)


Bills vs. Jets prediction & best bet

Bills -7.5 (+100 via FanDuel)

Admittedly, this is a big number, just beyond the key -7 mark. However, the Bills are rolling and have covered three of the previous four. They are 6-2 ATS and enter on the back of a 17-point victory over the Minnesota Vikings and their elite defense.  

The Bills boast the highest-scoring offense (32 points per game) and the third-best offensive DVOA. While their flawed defense took advantage of the Miami Dolphins and Vikings' bottom-five offenses, the Jets' attack scored more than 24 points just twice in nine games.

They scored 25 against the Dolphins' 26th-ranked offensive DVOA and 33 against the Las Vegas Raiders' 31st-ranked unit. They're also 2-7 and have almost no chance of making the playoffs. The Bills, meanwhile, have designs on bigger and better things, and I expect them to take no prisoners. 

📡 SBR Edge - Bills' recent dominance over the Jets

The Jets are 0-3 ATS in the last three and have lost five in a row to the Bills, four of which by at least 20 points. 

More worrying signs for the Jets 

The Jets' four-game losing streak hasn't been pretty, as they've allowed 32 points per game. While I'm not saying the team has entirely quit on head coach Aaron Glenn, that eventuality feels close.

And if you take their highest two scores out of the equation, the Jets average 15 points per game. Entering a game against arguably the league's best offense with both sides of the ball floundering is particularly ominous. 

Play to: Bills -9

Score prediction: Bills 31, Jets 21


Live Bills vs. Jets odds

See the latest odds movement and more on our Bills vs. Jets page. 

Bills vs. Jets opening odds

  • Moneyline: Bills (-474) | Jets +375
  • Spread: Bills -8.5 (-110) | Jets +8.5 (-108)
  • Over/Under: Over 49.5 (-108) | Under 49.5 (-110)

Bills vs. Jets weather

It will be about 48 degrees at kickoff, with winds up to about 13 miles per hour. There is no chance of precipitation. 


Latest Bills vs. Jets injuries


How to watch Bills vs. Jets: Week 10

  • Date: Sunday, Nov. 15
  • Kickoff: 1 p.m. ET
  • Location: MetLife Stadium (East Rutherford, N.J.)
  • TV/Streaming: CBS, Fubo