Patriots vs. Lions Prediction: Week 10 Odds, Picks & Best Bet (Nov. 15)
Sunday's games kick off at Allianz Arena in Munich, Germany (9:30 a.m. ET, FOX), and I'm backing the Over as part of my Patriots vs. Lions prediction.
The Lions have won four in a row and are the 2.5-point betting favorite, while the Patriots enter on the back of two defeats in their last three. The analysis below explains why I believe we will enjoy an offensive game with at least 51 points.
Patriots vs. Lions picks & predictions
See all of our experts' NFL picks for Week 10 based on the latest NFL odds.
| Pick | Odds | Bet size |
|---|---|---|
| Lions -2.5 | -118 via BetMGM | 1 unit to profit 0.85 |
| Over 50 | -111 via BetMGM | 1 unit to profit 0.9 |
Picks submitted: Friday, Nov. 13 at 6 a.m. ET. Odds subject to change.
Total wagered: 2 units | Profit if all picks win: 1.75 units
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Patriots vs. Lions prediction & best bet
Over 50 (-111 via BetMGM)
The Patriots averaged 29 points per game over the previous six, and the Lions are the fifth-highest scoring team, averaging 27.8. I'm not letting the Lions' three successive Unders deter, as Dan Campbell's team faced two of the four worst offenses via DVOA (Miami and Minnesota). It's one of the primary reasons the Lions' defense hasn't allowed more than 17 points in the last three games.
And New England's defense has allowed 31.3 points per game over the previous three. The only game in which they didn't allow at least 30 points in that sample was against the Miami Dolphins and their anemic offense.
📡 SBR Edge - Over reigns supreme
The Lions are 5-3 to the Over while the Patriots are 6-3. Only one team, the Las Vegas Raiders, have been in more Overs (7).
Lions due for a high-scoring game
The Lions have played in three straight Unders for the first time since the opening three games of the 2024 season. Detroit hasn't been involved in four straight Unders since the 2021 campaign, when it finished a woeful 3-13-1.
Play to 52: I'd play the Over to 52 points before considering the Under.
Score prediction: Lions 30, Patriots 27
Live Patriots vs. Lions odds
See the latest odds movement and more on our Patriots vs. Lions page.
Patriots vs. Lions opening odds
- Moneyline: Patriots (+100) | Lions (-120)
- Spread: Patriots +1.5 (-115) | Lions -1.5 (-105)
- Over/Under: Over 48.5 (-110) | Under 48.5 (-110)
Patriots vs. Lions weather
It should be clear with almost no wind and about 46 degrees at kickoff. There is a 5% chance of rain, but the conditions should be excellent, if not ever so slightly cool.
Latest Patriots vs. Lions injuries
How to watch Patriots vs. Lions: Week 10
- Date: Sunday, Nov. 15
- Kickoff: 9:30 a.m. ET
- Location: Allianz Arena (Munich, Germany)
- TV/Streaming: FOX
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