Skip to main content
We're backing Michigan State in our Michigan State vs. Iowa prediction.
Pictured: Michigan State guard Jaden Akins dribbles the ball against USC. Photo by William Navarro via Imagn Images.

March has arrived, and so has Michigan State’s momentum. Tom Izzo’s Spartans (24-5, 15-3 Big Ten) are peaking at the perfect time, riding a five-game win streak into Thursday’s showdown.

They’ll hit the road to face the Iowa Hawkeyes (15-14, 6-12) at Carver-Hawkeye Arena, with tipoff set for 8 p.m. ET on Fox Sports. Michigan State enters as a 6.5-point favorite.

Our Michigan State vs. Iowa prediction, odds, and expert picks break down whether the Spartans can keep rolling or if the Hawkeyes can pull off the upset at home.

📈 Michigan State vs. Iowa odds movement

Michigan State opened as a 7 to 7.5-point road favorite with the line shifting down to Spartans -6.5 as tip approaches tonight. With Izzo's team's recent dominance of the Big Ten, 66% of the public is backing Sparty to take down Iowa.

💰 Michigan State vs. Iowa predictions, expert picks & best bets tonight

Here are my best Michigan State vs. Iowa predictions, expert picks, and best bets tonight with my pick confidence based on a 1-to-5-star scale. Be sure to check out the rest of our college basketball picks along with our guide on how to bet on college basketball.

  • Against the spread pick: Michigan State -6.5 (-112 via DraftKings) vs. Iowa ⭐⭐
  • My best player prop bet: Payton Sandfort Under 2.5 made 3-pointers (-150 via bet365) ⭐⭐⭐⭐
  • Exact score prediction: Michigan State 82, Iowa 72 (+15000 via DraftKings) ⭐

🏀 Michigan State vs. Iowa ATS prediction & best player prop bet pick

Here's why I'm betting on Michigan State to cover the spread (-6.5) while targeting Payton Sandfort Under 2.5 made 3-pointers as my best player prop bet pick for tonight:

✅ Michigan State to cover the spread (-6.5) ⭐⭐

This line has climbed up to -7 at most of our best sports betting sites, so it’s worth grabbing the current line before it’s too late. Most college basketball projection systems expect the Spartans to cover this number:

There is some quit potential with the Hawkeyes after losing four of their past five and seven of their last nine outings. There is a chance the Spartans roll on Thursday, especially after covering the spread in five straight games.

📊 Best odds: -112 via DraftKings (bet $10 to win $8.93)

Bet $5, Get $200 + $1K Deposit Bonus

Terms and conditions apply.

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission. 21+. Gambling can be addictive, please play responsibly

🔥 Payton Sandfort ⭐⭐⭐⭐

Iowa forward Payton Sandfort has hit two 3-pointers over his past three games, attempting 15 shots over that span. However, a matchup against Michigan State isn’t the right time to break out of a shooting slump.

The Spartans are fourth in defensive 3-point percentage, allowing opponents to shoot 28.2% from long range. They have the fifth-ranked defensive efficiency in the country.

This line is as high as -170 at our best sports betting apps, indicating this bargain at bet365.

📊 Best odds: -150 via bet365 (bet $10 to win $6.67)

Bet $5, Get $150 in Bonus Bets Win or Lose*

*Deposit required. Mobile app only. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply. Gambling problem? Call 1-800-GAMBLER

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission. 21+. Gambling can be addictive, please play responsibly

🎯 Expert Michigan State vs. Iowa score prediction 

🔮 Expert score prediction: Michigan State 82, Iowa 72

With two games left in the regular season, it’s essential to identify which teams are playing well entering the tournament and which teams are ready for the offseason. There is a chance this game features one of each, so I expect Michigan State to cruise past Iowa for an 82-72 road victory.

📊 Best odds: +15000 via DraftKings (bet $10 to win $1,500)

📊 Live Michigan State vs. Iowa odds & latest betting splits

Here are the latest odds for Michigan State vs. Iowa, which update live in real time. You can also check out our NEW college basketball player prop odds tool for the latest college basketball odds on any market across legal sportsbooks in your region.

🔢 Michigan State vs. Iowa opening odds

Here's a look at the opening odds for Michigan State vs. Iowa according to BetMGM.

  • Spread: Michigan State -7.5 (-105) | Iowa +7.5 (-115)
  • Moneyline: Michigan State -300 | Iowa +240
  • Over/Under: Over 151.5 (-110) | Under 151.5 (-110)

🏆 Who will win Michigan State vs. Iowa?

As of 9:15 a.m. ET, Michigan State is favored by 6.5 points to beat Iowa with moneyline odds of -285 at BetMGM, which suggests a 74.3% win probability for the Spartans. We're predicting an 82-72 win for Michigan State as our final score projection.

So far, 68% of bettors have wagered against the spread on Michigan State -6.5, while 51% of bettors expect the game to finish Over the projected total of 151.5 points.

📺 How to watch Michigan State vs. Iowa tonight

📅 Date: Thursday, March 6, 2025
🕗 Time: 8 p.m. ET
📍 Location: Carver-Hawkeye Arena (Iowa City)
📺 TV: Fox Sports
💻 Streaming: Fox Sports App

❓ Michigan State vs. Iowa FAQs

Who is favored to win Michigan State vs. Iowa?

Michigan State is -285 to win, translating to an implied probability of 74.3%.

What are the betting odds for Michigan vs. Iowa?

The latest spread is Michigan State -6.5 (-115) | Iowa +6.5 (-105), with a total of 151.5 points.

What will be the final score of Michigan State vs. Iowa?

We're predicting a final score of Michigan State 82, Iowa 72, entering tonight's matchup at Carver-Hawkeye Arena.

What time is Michigan State vs. Iowa tonight?

Michigan State vs. Iowa will begin tonight at 8 p.m. ET.

⛹️ Best college basketball betting sites

Looking to bet on college basketball tonight? Here are our best March Madness betting sites as determined by our expert team at Sportsbook Review, along with our best March Madness betting promos ahead of the NCAA Tournament.

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission