USC vs. Wisconsin Prediction: Week 8 Odds, Picks & Best Bet (Oct. 24)

Our USC vs. Wisconsin prediction for Week 8 includes our best bet, projected score, and the latest odds for Saturday's matchup.
Southern California Trojans quarterback Jayden Maiava (14) looks to throw a pass as he is featured in our USC vs. Wisconsin prediction.
Pictured: Southern California Trojans quarterback Jayden Maiava (14) looks to throw a pass as he is featured in our USC vs. Wisconsin prediction. Photo by Matthew O'Haren-Imagn Images
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A Big 10 clash in the Midwest has a home underdog hosting a prolific offense for my USC vs. Wisconsin prediction. 

No. 16 USC, led by QB Jayden Maiava, is seeking its second straight conference road win following a 31-23 victory over Penn State. Wisconsin looks to remain undefeated at home, as the Badgers are +2.5 in Camp Randall Stadium in Madison, Wis., with kickoff set for 7:30 p.m. ET (NBC). 


USC vs. Wisconsin picks & predictions

See all of our experts' college football picks for Week 8 based on the latest college football odds.

Pick Odds Bet size
Wisconsin +2.5  (+103 via bet365) 1.00 unit to profit 1.03 units
Under 50.5 (-110 via FanDuel) 2.20 units to profit 2.00 units

Picks submitted: Oct. 22 at 10:00 a.m. ET. Odds subject to change.

Total wagered: 3.20 units | Max profit: +3.03 units

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USC vs. Wisconsin prediction & best bet

Check out all of our college football predictions for more analysis across this week's slate.

Under 50.5 (-110 via FanDuel)

The Badgers, under fifth-year head coach Luke Fickell, are a top-25 scoring defense in the country. Wisconsin's defense held No. 9 UCLA to 17 points, however, its anemic offense couldn't muster much against a stout Bruins group.

USC's 26th-ranked offense will face its toughest test of the season on the road in Madison on Saturday night. Maiava has not scored more than 31 points against 3 straight conference opponents, while head coach Lincoln Riley's run game has only logged 1 rushing touchdown during this stretch. 

Wisconsin has held opponents to 1 passing touchdown in its last 5 games played. The Badgers are air-tight in the secondary, while holding the opposing run game to 3.2 YPC and 5 rushing touchdowns against 4 Power 4 teams that include No. 4 Notre Dame and No. 9 UCLA. 

USC has been better defensively lately, limiting opponents to 3.5 YPC or less and 2 total rushing touchdowns. Wisconsin's passing attack is not a big threat, logging under a 50 percent completion rate in 3 straight contests. 

Go to FanDuel and bet Under 50.5 at -110 odds. 

📡 SBR Edge: We Do Need The Stinkin' Badgers

Each of Wisconsin's last 9 home games played against Big 10 opponents has gone Under the total points line. 

Maiava's Trojans Upset By Stingy Badgers Defense

Wisconsin is going to wind up winning this game with its stingy defensive effort. USC's offense is not nearly as potent as it's been during Lincoln Riley's tenure, and now, the Badgers enter having only allowed 20 points or less in 5 straight outings. 

USC's defense is a bit improved but not great. Expect Wisconsin to force Maiava into turnovers or miscues, leading to empty possessions and momentum swings that the Badgers can leverage into points. Wisconsin upsets USC for its biggest win in 2026. 

Play to: Under 47.5  

Score prediction: Wisconsin 24, USC 23


Live USC vs. Wisconsin odds

See the latest odds movement and more on our [team vs. team matchup] page. (** link to the page for the associated game found at: https://www.sportsbookreview.com/betting-odds/college-football/ ** )

USC vs. Wisconsin opening odds

  • Moneyline: USC -133 | Wisconsin +112
  • Spread: USC -1.5 (-115) | Wisconsin +1.5 (-105)
  • Over/Under: Over 52.5 (-108) | Under 52.5 (-112)

USC vs. Wisconsin weather

Saturday night's forecast at Camp Randall Stadium calls for a warm 63 degrees and a 0 percent probability of precipitation. However, 11.2 mph winds are expected and could make an impact on passing and kicking attempts. 


Latest USC vs. Wisconsin injuries

  • USC TE Mark Bowman - questionable

How to watch USC vs. Wisconsin: Week 8

  • Date: Saturday, Oct. 24
  • Kickoff: 7:30 p.m. ET
  • Location: Camp Randall Stadium (Madison, Wis.)
  • TV/Streaming: NBC