Wyoming probably wins outright, Toledo is NOT a good team and they are now home favorites after 3 straight upset wins. A profitable angle over the years is to play against any favorite coming off of an upset win, so I guess that would be triply true here. 
Reason Toledo is not good is that they are only averaging 260 yards per game, Only reason they won three straight is opponents committed an incredible 13 turnovers in the 3 games.

Reason Toledo is not good is that they are only averaging 260 yards per game, Only reason they won three straight is opponents committed an incredible 13 turnovers in the 3 games.