| Score | Score | ||||||||
| Eagles @ | -7 -120 | O40.5 -108 | -410 | 23 | Rams @ | -7.5 -110 | O44.5 -110 | -380 | 26 |
| Giants | (+7) (+100) | U40.5 -112 | (+320) | 16 | Ravens | (+7.5) -110 | U44.5 -110 | (+300) | 13 |
| Broncos @ | -7.5 -105 | O43.5 -115 | -395 | 31 | Titans @ | (+4.5) -112 | O41.5 -112 | (+190) | 20 |
| Jets | (+7.5) -115 | U43.5 -105 | (+310) | 10 | Raiders | -4.5 -108 | U41.5 -108 | -230 | 26 |
| Cardinals @ | (+7) -108 | O46.5 -118 | (+270) | 26 | Bengals @ | (+14) -105 | O44.5 -110 | (+700) | 17 |
| Colts | -7 -112 | U46.5 -102 | -340 | 33 | Packers | -14 -115 | U44.5 -110 | -1100 | 38 |
| Chargers @ | -4.5 -108 | O44.5 -102 | -225 | 27 | 49ers @ | (+3) -105 | O47.5 -110 | (+130) | 24 |
| Dolphins | (+4.5) -112 | U44.5 -118 | (+185) | 24 | Bucs | -3 -115 | U47.5 -110 | -155 | 27 |
| Patriots @ | -3.5 -105 | O45.5 -120 | -185 | 28 | Lions @ | (+2.5) -110 | O52.5 -115 | (+114) | 30 |
| Saints | (+3.5) -115 | U45.5 (+100) | (+154) | 20 | Chiefs | -2.5 -110 | U52.5 -105 | -135 | 33 |
| Browns @ | (+5.5) -115 | O37.5 -115 | (+205) | 16 | Bills @ | -4.5 -115 | O49.5 -118 | -230 | 34 |
| Steelers | -5.5 -105 | U37.5 -105 | -250 | 21 | Falcons | (+4.5 -105) | U49.5 -102 | (+190) | 23 |
| Cowboys @ | -3 -120 | O49.5 -112 | -180 | 31 | Bears @ | (+4.5 -105) | O49.5 -110 | (+185) | 20 |
| Panthers | (+3 +100) | U49.5 -108 | (+150) | 24 | Commanders | -4.5 -115 | U49.5 -110 | -225 | 27 |
| Seahawks @ | (+1.5) -112 | O47.5 -110 | (+100) | 20 | BYE | ||||
| Jaguars | -1.5 -108 | U47.5 -110 | -120 | 14 | Vikings | Texans | |||