| HOME | WINNING % | AWAY | WINNING % |
| Cincinnati Bengals | 44.44% | Houston Texans | 55.56% |
| Baltimore Ravens | 54.84% | Cleveland Browns | 45.16% |
| Carolina Panthers | 41.38% | Buffalo Bills | 58.62% |
| Indianapolis Colts | 51.85% | Arizona Cardinals | 48.15% |
| Jacksonville Jaguars | 72.41% | Tennessee Titans | 27.59% |
| Kansas City Chiefs | 44.83% | Philadelphia Eagles | 55.17% |
| New Orleans Saints | 93.10% | New England Patriots | 6.90% |
| Pittsburgh Steelers | 51.85% | Minnesota Vikings | 48.15% |
| Tampa Bay Buccaneers | 74.19% | Chicago Bears | 25.81% |
| Los Angeles Chargers | 6.90% | Miami Dolphins | 93.10% |
| Oakland Raiders | 100.00% | New York Jets | 0.00% |
| Denver Broncos | 13.79% | Dallas Cowboys | 86.21% |
| Los Angeles Rams | 61.29% | Washington Redskins | 38.71% |
| Seattle Seahawks | 77.78% | San Francisco 49ers | 22.22% |
| Atlanta Falcons | 54.84% | Green Bay Packers | 45.16% |
| New York Giants | 27.59% | Detroit Lions | 72.41% |
| STRAIGHT UP |
| Houston Texans |
| Baltimore Ravens |
| Buffalo Bills |
| Indianapolis Colts |
| Jacksonville Jaguars |
| Philadelphia Eagles |
| New Orleans Saints |
| Pittsburgh Steelers |
| Tampa Bay Buccaneers |
| Miami Dolphins |
| Oakland Raiders |
| Dallas Cowboys |
| Los Angeles Rams |
| Seattle Seahawks |
| Atlanta Falcons |
| Detroit Lions |
| UNDERDOGS |
| Houston Texans +5.5 |
| Buffalo Bills +7 |
| Indianapolis Colts +7 |
| Jacksonville Jaguars +1 |
| Philadelphia Eagles +5 |
| New Orleans Saints +6 |
| Miami Dolphins +3.5 |
| Detroit Lions +3 |
| BEST BETS |
| New Orleans Saints +6 |
| Miami Dolphins +3.5 |
