I love the Cardinals in this spot. They have one of the deepest teams in the country and over the course of this year I think they will establish themselves as a true national championship contender. Giving 8.5 to a good Vandy team seems like a lot but Louisville should get the job done here. Lay the points with the Cards here.
Louisville -8.5 -110 (3x)
Edit: Add Florida +6 -110 for 5 Units.
Louisville -8.5 -110 (3x)
Edit: Add Florida +6 -110 for 5 Units.