Patriots vs. Seahawks Expert Picks for NFL Kickoff: NFL Week 1 Predictions

Our Patriots vs. Seahawks expert picks feature our NFL experts with their favorite predictions for the NFL kickoff.
Seattle Seahawks quarterback Sam Darnold sets to pass as we make our Patriots vs. Seahawks expert picks
Pictured: Seattle Seahawks quarterback Sam Darnold sets to pass as we make our Patriots vs. Seahawks expert picks. Photo by Mark J. Rebilas-Imagn Images
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At long last the NFL is returning, and we have you covered for the opening game of the season with our Patriots vs. Seahawks expert picks. When play gets underway from Lumen Field in Seattle at 8:20 p.m. ET we'll be treated to our third season-opening Super Bowl rematch, and our first Wednesday game since 2020.

Despite Seattle winning 29-13 in February, our experts are torn on who is the right side of the spread tonight. Seattle is lined as a 3.5-point betting favorite, with the action set to air on NBC.


🏈 Patriots vs. Seahawks expert picks: NFL kickoff

See all of our experts' NFL picks based on the latest NFL odds.

Expert Pick Best odds
Mike Spector Patriots +3.5 -112 via FanDuel
Corey Scott Seahawks -3.5 -104 via FanDuel
LJ Blut Patriots +3.5 -118 via FanDuel
Quinn Allen Patriots +3.5 -119 via FanDuel
C Jackson Cowart Seahawks -3.5 -104 via FanDuel

Mike Spector's pick: Patriots +3.5 

The Seahawks defense recorded six sacks and three takeaways in the Super Bowl despite a 15% blitz rate. Even if Drake Maye is under pressure again, as he was on 34% of his dropbacks (ninth-highest), he still led the NFL in Total QBR (77) while under much duress.   

See Mike Spector's full analysis in his Patriots vs. Seahawks prediction.

Corey Scott's pick: Seahawks -3.5

The Seahawks closed as a 5.5-point betting favorite in Super Bowl LX before winning by 16 points. Yes, the Patriots have made more noise in the offseason by bringing in A.J. Brown. However, neither team has changed enough for the spread to drop to 3.5 in Seattle.

LJ Blut's pick: Patriots +3.5

Seattle no longer has Kenneth Walker III, while its rushing attack must rely on less-established options.  New England can keep this game close behind Drake Maye, making Patriots +3.5 the side to back.  

Quinn Allen's pick: Patriots +3.5

The Patriots look appealing as 3.5-point underdogs against a Seattle offense facing some early uncertainty. Super Bowl MVP Kenneth Walker III departed for Kansas City, while Zach Charbonnet remains sidelined, leaving the Seahawks thin in the backfield. Meanwhile, New England strengthened its roster considerably, most notably adding A.J. Brown and Romeo Doubs to give Drake Maye an improved receiving corps.

C Jackson Cowarts's pick: Seahawks -3.5

I can understand the appeal with the Patriots, who are a better team on paper than they were ahead of that slaughter in February. But the Seahawks still have Mike Macdonald calling plays for the most terrifying defense in football, and the 12s will be in full earthquake mode for this Super Bowl rematch.


💰 More Patriots vs. Seahawks picks & predictions


📺 How to watch Patriots vs. Seahawks: NFL Kickoff

  • Date: Thursday, Sept. 9
  • Kickoff: 8:20 p.m. ET
  • Location: Lumen Field (Seattle)
  • TV: NBC

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